Management of Bradyarrhythmias in Heart Failure: A Tailored Approach

Abstract

Patients with heart failure (HF) may develop a range of bradyarrhythmias including sinus node dysfunction, various degrees of atrioventricular block, and ventricular conduction delay. Device implantation has been recommended in these patients, but the specific etiology should be sought as it may influence the choice of the type of device required (pacemaker vs. implantable cardiac defibrillator). Also, pacing mode must be carefully set in patients with heart failure (HF) and left ventricular systolic dysfunction.In this chapter, we summarize the knowledge required for a tailored approach to bradyarrhythmias in patients with heart failure.

Risk Stratification of Sudden Cardiac Death in Patients with Heart Failure: An update

“…For example, in inherited dilated cardiomyopathy lamin, A/C and desmin mutation carry an increased risk of SCD [ 88 , 89 , 90 ].…”

Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity

“…8 There are a total of 7 million HFpEF patients, of them 80% present an obesity phenotype 9 and two-thirds of HFpEF patients develop arrhythmia either before, after, or during the diagnostic progression. 10,11 In the majority of HFpEF patients, aging is a common, universal, and inevitable factor that overlaps with obesity. Thereby, the impact of age-related obesity on cardiac health remains of interest.…”