Managing Vesicant Extravasations

Schulmeister, Lisa

doi:10.1634/theoncologist.2007-0191

Cited by 41 publications

(28 citation statements)

References 10 publications

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“…Preventive measures are strongly advocated in the the nurse (4,(7)(8) . However, in this study it was not possible to identify preventive measures established by the nursing team in their records, except for the complaints of women during infusion.…”

Section: Resultsmentioning

confidence: 99%

“…Although there is no consensus about localized drug use, the local application of ice for all drugs, except for the vinca alkaloids and oxaliplatin, when heat should be used, is an empirical measure used for many years, but with no evidence of benefits (7)(8)(9) . The protocol used in the service where this study was conducted is consistent with that suggested in the international literature, except for the use of sodium bicarbonate, which has not been recommended for its vesicant effect when given outside the vessel (8)(9) .…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Gozzo

Panobianco

Clapis

et al. 2010

Rev. Latino-Am. Enfermagem

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Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy TreatmentThis study aimed to analyze the occurrence of skin toxicity caused by drugs used in the protocol of neoadjuvant and adjuvant chemotherapy among women with breast cancer.Patient records of 72 women who were subject to this therapy between 2003 and 2006 were assessed. Of the 558 cycles of chemotherapy, 152 adverse events were registered.There were 37 registrations of dermatological toxicity, of those, 20 were extravasations that affected 17 women. Nine reports of hardened local injury, local fibrosis, pain, and hyperemia were registered during neoadjuvancy. In adjuvancy, among the 11 extravasations registered there were reports of hardened local injury, fibrosis and local pain. Lack of follow-up records for both periods was observed. Registration of the events and reports by the nursing team are essential to monitor the sites of venous puncture during the chemotherapy treatment, besides measuring and making a photographic record of the site.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Gozzo

Panobianco

Clapis

et al. 2010

Rev. Latino-Am. Enfermagem

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“…Hastaya kemoterapi tedavisine başlanma-dan önce kemoterapinin yan etkileri, komplikasyonları, riskleri, yararları, fizyolojik ve psikolojik etkileri hakkında bilgilendirme yapılmalıdır (10,19 …”

Section: Hasta Eğitimiunclassified

Periferal İntravenöz Kemoterapi Uygulamasına Yönelik Hemşirelik Yönetimi

Özkaraman¹,

Yeşilbakan²

2015

Osmangazi̇ Journal of Medicine

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ÖZET: Kemoterapi ilaçlarının intravenöz (IV) yolla uygulanmasında infiltrasyon ve ekstravazasyon gibi istenmeyen durumların yanı sıra flebit, hava embolisi, kanama ve hematom, enfeksiyon gibi bazı komplikasyonlar da gelişebilmektedir. IV tedavi uygulamalarından sorumlu olan hemşireler uygulama esnasında ne kadar dikkatli davranırlarsa da bu komplikasyonlar hala önlenemeyen bir sorun olarak karşımıza çıkmaktadır. Kemoterapi uygulamasında bilgili ve yetenekli bir hemşire tarafından doğru girişimlerin uygulanması bu komplikasyonların önlenmesinde ve yönetiminde en önemli kontrol edilebilir faktördür.ANAHTAR KELİMELER: IV kemoterapi tedavisi, komplikasyon, hemşire ABSTRACT: Complications which unlikely events such as infiltration, extravasation as well as phlebitis, air embolism, hemorrhage and hematoma, infections may occur in the intravenous administration of chemotherapy drugs. Although nurses who are responsible for intravenous therapy applications how careful being, these complications cannot always be prevented. Implementation of interventions by knowledgeable and skilled nurses in the intravenous chemotherapy towards the prevention and manangement of these complications is the most important factor which can be controlled.

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“…Mrs. Zatkó reported complications with "no serious consequences" (but not precisely determined) in case of 0.1 %, but the incidence of all events is not detailed 2 . The risk of extravasation can be reduced significantly by using centrally vein accessed ports and subcutaneously implanted "reservoirs" (subcutaneously implanted ports), but using this method cannot even guarantee to avoid this complication and in addition to the effects of cytostatic agents escaping into the tissues centrally, also unusual complications may develop [5,10,11,[18][19][20][21][22][23][24][25][26][27] .…”

Section: Incidence Of Extravasation and The Possibility Of Risk Incrementioning

confidence: 99%

Overview of extravasation management and possibilities for risk reduction based on literature data

Pikó¹,

Laczó²,

Szatmári³

et al. 2013

JNEP

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Background: The escape of cytostatic drugs from the blood vessels (paravasation, extravasation) during peripheral intravenous administration is a relatively frequent complication; in the United States of America it is reported in seven percent of cases with different severity and consequences. Although methods to completely avoid this complication are still unavailable, we are able to decrease its risk by identifying the patient and procedure-related factors. Methods:In this article the risk factors of extravasation, its prevention possibilities and in case of its development the available treatment choices will be reviewed based on the relevant literature data. Conclusion:The patient -if he/she was adequately informed -is a good indicator of extravasation therefore in case of patient's cooperation was not reliable due to any reason a closer nursing surveillance is required. The severity of tissue injury depends mainly on the chemical structure of the substance escaping from the blood vessels into the surrounding tissues (vesicant, irritant or non-vesicant) which may be modified by other factors as well. There are no high-level evidences available for the management of this complication, immediate discontinuation of the infusion and making an attempt to draw back the escaped drug through the cannula, elevation and immobilization of the affected extremity are required. Literature is contradictory about cooling or warming of the affected area and similarly there are still open questions regarding the value of using antidotes (dexrazoxane, dimethylsulfoxide, thiosulfate and hyaluronidase). If extravasation occurs early referral to dermatologist and surgeon is inevitable for definitive diagnosis and choosing the optimal management.

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Managing Vesicant Extravasations

Cited by 41 publications

References 10 publications

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Dermatological Toxicity in Women With Breast Cancer Undergoing Chemotherapy Treatment

Periferal İntravenöz Kemoterapi Uygulamasına Yönelik Hemşirelik Yönetimi

Overview of extravasation management and possibilities for risk reduction based on literature data

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