Manganese complexes displaying superoxide dismutase activity: A balance between different factors

Iranzo, Olga

doi:10.1016/j.bioorg.2011.02.001

Cited by 158 publications

(115 citation statements)

References 152 publications

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“…The standard electrode potential of the cerium species in the case of Ce 3+ /Ce(OH) 4 Green zone shows data for the "ideal" O − 2 dismutation catalyst [23,24]. Calculated values of the redox potential of stoichiometric and nonstoichiometric CDN at pH 7.0 (lower part) This result confirms the authors' conclusions [18] that cerium dioxide nanoparticles having a high concentration of trivalent cerium possess high SOD-like activity.…”

Section: Figsupporting

confidence: 78%

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Cerium dioxide nanoparticles as third-generation enzymes (nanozymes)

Попов¹,

Shcherbakov²,

Zholobak³

et al. 2017

Nanosystems: Phys. Chem. Math.

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Ceria nanoparticles are capable of performing the function of some enzymes (such as oxidoreductases, phosphatase) and can be classified as nanozymes. In this review, the actual data on the enzymatic activity of ceria were critically analyzed and specific conditions under which the cerium dioxide nanoparticles can act as enzymes were defined. The presented analysis may be useful in the planning, design and synthesis of ceria nanoparticles having the desired enzymatic functions required for various processes, including the development of the nanodrugs, which exhibit the therapeutic effect depending on their composition and pH of media, development of molecular sensors and biosensors, etc.

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Section: Figsupporting

confidence: 78%

“…The electrode potential of the superoxide radical dismutation at pH 7.0 in the case of the oxidation reaction is E = −0.16 V, in the case of the reduction reaction is E = +0.89 V (relative to the standard hydrogen electrode) [23,24].…”

Section: Figmentioning

confidence: 99%

Cerium dioxide nanoparticles as third-generation enzymes (nanozymes)

Попов¹,

Shcherbakov²,

Zholobak³

et al. 2017

Nanosystems: Phys. Chem. Math.

View full text Add to dashboard Cite

show abstract

“…Mitochondrial targeting with peptide mimetics or lipophilic cationic agents (MitoQ, SkQ1) or manganese superoxide (SOD2) mimetics (Pucheu et al, 1996;van Empel et al, 2006;Kawakami et al, 2009;Iranzo, 2011) may also offer therapy for mitochondrial antioxidant protection. However, strategies to direct these compounds to the organ or cell type of interest at the apposite time are lacking, and their impact on the redoxregulation of mitochondrial biogenesis is unknown.…”

Section: Other Compounds That Protect Mitochondria Through Mitochomentioning

confidence: 99%

Mitochondrial Quality Control as a Therapeutic Target

2015

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“…7). Although this method has some drawbacks [40], it is very commonly used, and therefore allows a comparison with a number of similar systems. The determined IC 50 values are listed in Table 3 Among the five most stable structures for CuH 2 L three have {NH 2 ,3N im } donor set (Table S1), also suggested by the experimental data.…”

Section: At Two-fold Excess Of Ligand Over the Metal Ion Bis-complexesmentioning

confidence: 99%