Manic Episode as a Rare Neuropsychiatric Manifestation of Systemic Lupus Erythematosus: Case Report

Abstract

Systemic lupus erythematosus (SLE) is a pathology capable of affecting several organs and systems of the human body, including the central nervous system. The most common psychiatric manifestations addressed in studies are acute confusional state, mood disorders, cognitive dysfunction, psychosis, among others. However, there are few documented case reports associating lupus with an episode of mania, mainly because this neuropsychiatric symptom usually precedes the onset of typical SLE symptoms, such as malar rash or arthralgias. The objective of this study is to describe the case of a patient hospitalized for diagnostic investigation of SLE who presented with mania.