Malaria, visceral leishmaniasis and yellow fever, today among some of the main vector diseases are known as control; the risk of diseases, its zoonotic and has been affected by forest destruction, risk characteristics, which non-biologically occupy Goiás, mostly occupy the state of Goiás. Thus, we seek to understand this relationship, through data available on official platforms. Where the study revealed that the largest municipality of cases of elaborated diseases is in the municipality of Goiânia for three cases of elaborated diseases when considered in the intermediate region, it is not the highest prevalence of the same. There is a greater concentration of diseases in the central and northern regions of the state. When confronted with the different land uses after 1985, savanna cases for both malaria and malaria increased the urban encounter to reduce land and increase structure. Already confronting the period of land use 2007, it did not occur that the cases of malaria in the municipalities that are necessary for the use and for leishmaniasis in the largest post-use regions for the urban area. It demonstrates, therefore, that the State is turning to activities that end up devastating more and more the cerrado, which probably culminates in vector migrations to an area and peri-urban that has increasingly presented territorial and population growth, or that is, diseases that were mostly rural, have been urbanizing in the face of anthropization of the cerrado.