Mapping of Contralateral Space in Retinotopic Coordinates by a Parietal Cortical Area in Humans

Sereno, Martin I.; Pitzalis, Sabrina; Martı́nez, Antı́gona

doi:10.1126/science.1063695

Cited by 630 publications

(633 citation statements)

References 39 publications

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“…The topology of visual space is preserved to some degree in these maps, in that neighboring patches of cortex represent neighboring parts of the visual field, forming continuous maps across the cortical surface. A similar mapping of contralateral visual space across the cortical surface was recently revealed in the putative human lateral intraparietal area (LIP), located in posterior parietal cortex (Sereno et al, 2001). Unlike the maps in many earlier visual areas, however, this map only became evident when the subject was required to engage attention and working memory.…”

Section: Introductionmentioning

confidence: 55%

“…Outlines of the ROIs defined based on group average block design data are superimposed in green. P values from ROI-based t tests are shown in Table 1. phase-spread within these maps was not simply due to differences in hemodynamic delay, subjects were tested with both counterclockwise and clockwise stimulus revolution directions (Sereno et al, 1995(Sereno et al, , 2001. After reversing the phases of the clockwise runs to be consistent with counterclockwise runs, the resulting maps are quite similar, demonstrating that the phase-spreads are stimulusdriven (Fig.…”

Section: Resultsmentioning

confidence: 86%

“…including an fMRI study that identified a map in the putative human LIP (Sereno et al, 2001). Subjects were briefly presented with a small dot at one of eight peripheral locations.…”

Section: Discussionmentioning

confidence: 99%

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Spatial maps in frontal and prefrontal cortex

2006

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Section: Introductionmentioning

confidence: 55%

Section: Resultsmentioning

confidence: 86%

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Spatial maps in frontal and prefrontal cortex

2006

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“…From studies that examine the human IPS, it is apparent that the human region is also well positioned to play a key role in sensorimotor transformations. Functional connectivity analyses have shown a tight correlation between visual cortex and IPS activity during visuospatial processing (Kayser et al, 2010a;Sereno et al, 2001;Silver et al, 2005;Swisher et al, 2007), and manipulation of visuospatial or featurebased attention modulates IPS activity (Corbetta and Shulman, 2002;Kayser et al, 2010b, respectively). Further studies have also correlated IPS activity with evidence accumulation (Kayser et al, 2010a;Ploran et al, 2007) and motor intention (Hesse et al, 2006;Rushworth et al, 2003); and a number of studies investigating visuomotor control show activation within and around IPS (reviewed in Culham et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

The neural representation of sensorimotor transformations in a human perceptual decision making network

Erickson

Kayser

2013

NeuroImage

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Humans can quickly engage a neural network to transform complex visual stimuli into a motor response. Activity from a key region within this network, the intraparietal sulcus (IPS), has been associated with evidence accumulation and motor planning, thus implicating it in sensorimotor transformations. If such transformations occur within a brain region, a key and untested prediction is that neural activity reflecting both the parametric amount of evidence available and the timing of motor planning can be independently manipulated. To investigate these ideas, we constructed a dot motion discrimination task in which information about response modality (what to use) and response mapping (how to use it) was provided independently either before or after presentation of a dot motion coherence stimulus whose strength varied across trials. Consistent with our hypothesis, activity within IPS covaried with dot motion coherence during the stimulus phase, and as information necessary for the response was delayed, the peak of IPS activity shifted to the response phase. In contrast, areas such as the motion-sensitive region MT+ and the supplementary motor area demonstrated activity limited to the stimulus and response phases of the task, respectively. These results show that activity in IPS correlates with temporally dissociable representations consistent with both evidence accumulation and motor planning, and suggest that IPS is a core component for sensorimotor transformations within the perceptual decision-making network.© 2013 Elsevier Inc. All rights reserved. IntroductionThe ability to link sensation with action is integral to even the most fundamental of decisions. In humans, a number of studies have identified a frontoparietal network involved in processes during perceptual decisions, including sensory processing, attentional control, evidence accumulation, and motor planning (Heekeren et al., 2008; Kayser et al., 2010a,b;Liu and Pleskac, 2011;Ploran et al., 2007Ploran et al., , 2011Rowe et al., 2010;Ho et al., 2009;Tosoni et al., 2008). Previously we demonstrated that for subjects performing a dot motion discrimination task, this network displays a blood oxygen level-dependent (BOLD) response that varies inversely with motion coherence (Kayser et al., 2010a). Consistent with previous and subsequent findings (e.g., Hebart et al., 2012;Ho et al., 2009;Kayser et al., 2010b), this negative parametric effect matched predictions of a proportional-rate diffusion model for evidence accumulation to a threshold (Palmer et al., 2005;Ratcliff and McKoon, 2008), and linked human brain activity with a computational model of the transformation from stimulus to response.Although this parametric effect is necessary, it is not sufficient to define regions that support such sensorimotor transformations. Human studies, for example, show that areas such as the motion-sensitive region MT+, supplementary motor area (SMA), and intraparietal sulcus (IPS) all display this parametric effect. Importantly, results from macaque studies show that ...

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“…For example, the classical language areas in superior temporal cortex and frontal cortex are often considered to be non‐visual. However, in the last decade or so, several additional retinotopic maps were discovered in frontal cortex [Hagler and Sereno, 2006; Hagler et al, 2007; Kastner et al, 2007], parietal cortex [Huk et al, 2002; Schluppeck et al, 2005; Sereno and Huang, 2006; Sereno et al, 2001, 2003; Silver et al, 2005; Silver and Kastner, 2009; Swisher et al, 2007] and temporal cortex [Huang and Sereno, 2013; Sereno et al, 2003]. The higher‐level retinotopic maps in frontal cortex were originally discovered using working memory and spatial attention paradigms [Hagler and Sereno, 2006; Kastner et al, 2007].…”

Section: Discussionmentioning

confidence: 99%

Areas activated during naturalistic reading comprehension overlap topological visual, auditory, and somatotomotor maps

Sood

Sereno

2016

Human Brain Mapping

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Cortical mapping techniques using fMRI have been instrumental in identifying the boundaries of topological (neighbor‐preserving) maps in early sensory areas. The presence of topological maps beyond early sensory areas raises the possibility that they might play a significant role in other cognitive systems, and that topological mapping might help to delineate areas involved in higher cognitive processes. In this study, we combine surface‐based visual, auditory, and somatomotor mapping methods with a naturalistic reading comprehension task in the same group of subjects to provide a qualitative and quantitative assessment of the cortical overlap between sensory‐motor maps in all major sensory modalities, and reading processing regions. Our results suggest that cortical activation during naturalistic reading comprehension overlaps more extensively with topological sensory‐motor maps than has been heretofore appreciated. Reading activation in regions adjacent to occipital lobe and inferior parietal lobe almost completely overlaps visual maps, whereas a significant portion of frontal activation for reading in dorsolateral and ventral prefrontal cortex overlaps both visual and auditory maps. Even classical language regions in superior temporal cortex are partially overlapped by topological visual and auditory maps. By contrast, the main overlap with somatomotor maps is restricted to a small region on the anterior bank of the central sulcus near the border between the face and hand representations of M‐I. Hum Brain Mapp 37:2784–2810, 2016. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

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Mapping of Contralateral Space in Retinotopic Coordinates by a Parietal Cortical Area in Humans

Cited by 630 publications

References 39 publications

Spatial maps in frontal and prefrontal cortex

Spatial maps in frontal and prefrontal cortex

The neural representation of sensorimotor transformations in a human perceptual decision making network

Areas activated during naturalistic reading comprehension overlap topological visual, auditory, and somatotomotor maps

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