Mapping of quantitative trait loci and confirmation of the FAT1 region on chromosome 4 in an F2 population of pigs

Abstract

The objective was to map QTL on porcine chromosome 4 and to associate them with carcass and internal organ traits in an F2 population. The F1 population was produced by outbreed crossing, using two native Brazilian breed Piau boars and 18 commercial sows. A total of 617 F2 animals issued from 11 F1 boars and 54 F1 sows were typed for a total of five microsatellite markers. The data were analyzed by multiple regressions developed for the analysis of crosses between outbred lines, using the QTL Express software. Significant evidence for QTL was found for pig chromosome 4 regarding carcass and internal organ traits. All QTL were detected in the same region of the chromosome, designated FAT1.

Fine mapping and single nucleotide polymorphism effects estimation on pig chromosomes 1, 4, 7, 8, 17 and X

“…The QTL affecting CL was also detected by Große-Brinkhaus et al (2010) in a Duroc x Pietrain cross. The QTL for LBF that we found was also detected by Silva et al (2008) and Malek et al (2001). Piau alleles were estimated to increase backfat thickness as expected.…”

Using pedigree analysis to monitor the local Piau pig breed conservation program

“…The genetics underpinnings of the large fat deposition of Piau pigs have been explored in genetic studies by the Animal Breeding and Genetics group of the Federal University of Viçosa, Minas Gerais state, Brazil. These studies include QTL mapping using divergent crosses Paixão et al, 2008;Silva et al, 2008), polymorphism analysis of candidate genes (Band et al, 2005;Carmo et al, 2005;Faria et al, 2006;Peixoto et al, 2006), phylogeny and genetic diversity analyses (Sollero et al, 2009;Souza et al, 2009) and expression patterns of candidate genes (Sousa et al, 2011;Serão et al, 2011;Sollero et al, 2011).…”

Estimação de parâmetros genéticos de uma população F2 de suínos

“…Zhang et al (1998) realizaram mapeamento dos locos de características quantitativas em gado de leite e observaram que vários cromossomos, em particular o seis; nove; 14; 20 e 26, apresentaram locos de características quantitativas associados a mais de uma característica. Estudos têm relatado a identificação de locos de características quantitativas em suínos para uma variedade de características (SILVA et al, 2003a;SILVA et al, 2003b;GONÇALVES et al, 2005;PIRES et al, 2005PIRES et al, e 2008PAIXÃO et al, 2008a;SILVA et al, 2008;EDWARDS et al, 2008a,b, SILVA et al, 2009PINTO et al, 2010, GONG et al, 2010, SOUZA et al, 2011. A maioria desses estudos utilizaram cruzamentos entre raças divergentes e focaram características de crescimento, carcaça, cortes de carcaça, órgãos internos e qualidade de carne.…”