Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography

Abstract

Eyes affected by AAU demonstrate an increase in ChT before and a subsequent decrease after therapy while retinal thickness seems unaltered by disease and therapy. ChT might be a useful biomarker in monitoring posterior involvement and response to therapy in patients with AAU.

Optical coherence tomography and optical coherence tomography angiography in uveitis: A review

“…In the iris, OCTA can detect dilation of vessels during acute iridocyclitis, whereas retinal microvascular changes are visible in acute uveitis . An increase of the choroidal thickness can also be seen on OCT scans in most cases of uveitis, including those mainly affecting the anterior segment . This is an indirect measurement of increased blood flow within the choroid induced by the inflammation and can be monitored to evaluate the inflammatory status of the eye over time (Figure C,D).…”

“…In AU, the inflammatory process is mainly localized in the anterior chamber; nevertheless, recent evidence suggests that the choroidal blood flow may also be affected. Independent groups have reported that the thickness of the choroid, as measured by OCT, increases during the acute phases of AU . These changes disappeared when the inflammation was treated, suggesting that choroidal thickness assessment through OCT scans could be a useful tool in monitoring the response to therapy in these patients …”

“…Independent groups have reported that the thickness of the choroid, as measured by OCT, increases during the acute phases of AU. 14,27 These changes disappeared when the inflammation was treated, suggesting that choroidal thickness assessment through OCT scans could be a useful tool in monitoring the response to therapy in these patients. 14 OCTA has limited applications compared to structural OCT in AU.…”

“…14,27 These changes disappeared when the inflammation was treated, suggesting that choroidal thickness assessment through OCT scans could be a useful tool in monitoring the response to therapy in these patients. 14 OCTA has limited applications compared to structural OCT in AU. Dilation of the iris vessels detectable with OCTA has been reported during the acute phases of AU, with a disappearance of the changes after treatment.…”

The state of the choroid in children with anterior uveitis assessed by optical coherence tomography

“…Попытки оценить роль этого параметра при передних увеитах [7][8][9][10][11][12][13][14] дали противоречивые результаты. В ряде работ обнаружено увеличение толщины сосудистой оболочки в субфовеолярной и парафовеолярной зонах в период активности воспаления [8,10,[12][13][14], а H. Yan и соавт. [9] продемонстрировали ее уменьшение при неактивном переднем увеите.…”