Mapping the proteogenomic landscape enables prediction of drug response in acute myeloid leukemia

Pino, James C.; Posso, Camilo; Joshi, Sunil K.; Nestor, Michael; Moon, Jamie; Hansen, Joshua R.; Hutchinson-Bunch, Chelsea; Gritsenko, Marina A.; Weitz, Karl K.; Watanabe-Smith, Kevin; Long, Nicola; McDermott, Jason E.; Druker, Brian J.; Liu, Tao; Tyner, Jeffrey W.; Agarwal, Anupriya; Traer, Elie; Piehowski, Paul D.; Tognon, Cristina E.; Rodland, Karin D.; Gosline, Sara J.C.

doi:10.1016/j.xcrm.2023.101359

Cell Reports Medicine

2024

DOI: 10.1016/j.xcrm.2023.101359

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Mapping the proteogenomic landscape enables prediction of drug response in acute myeloid leukemia

James C. Pino,

Camilo Posso,

Sunil K. Joshi

et al.

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Cited by 2 publications

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Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets

Murray,

Sillar,

Chambers

et al. 2024

Expert Review of Proteomics

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Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets

Murray,

Sillar,

Chambers

et al. 2024

Expert Review of Proteomics

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Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies

Niscola,

Gianfelici,

Catalano

et al. 2024

Current Oncology

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Acute myeloid leukemia (AML) is a heterogeneous blood-related neoplasm that predominantly afflicts older adults with a poor prognosis due to their physical condition and the presence of medical accompanying comorbidities, adverse biological disease features, and suitability for induction intensive chemotherapy and allogenic stem cells transplantation. Recent research into the molecular and biological factors contributing to disease development and progression has led to significant advancements in treatment approaches for older patients with AML. This review article discusses the latest biological and therapeutic developments that are transforming the management of AML in older adults.

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Mapping the proteogenomic landscape enables prediction of drug response in acute myeloid leukemia

Cited by 2 publications

References 81 publications

Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets

Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets

Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies

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