Margin status is still an important prognostic factor in hepatectomies for colorectal liver metastases: A propensity score matching analysis

Méméo, Riccardo; Association, French Surgical

doi:10.1016/j.ejso.2018.01.068

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, most scholars continue to reject R1 resection. [40] R1 resection is believed to have a worse prognosis than R0 resection, and the DFS after surgery is shorter. [41][42][43][44] Since CRLM often occurs in multiple locations and has a high likelihood of recurrence after surgery, it is essential to preserve as much healthy liver tissue as possible while effectively removing the tumor.…”

Section: Discussionmentioning

confidence: 99%

Relationship between hepatic surgical margins of colorectal cancer liver metastases and prognosis: A review

Ai,

Zhang,

Jin

et al. 2024

Medicine

View full text Add to dashboard Cite

Colorectal cancer (CRC) remains a significant global health concern, as characterized by its high mortality rate ranking second among all the leading causes of death. The liver serves as the primary site of CRC metastasis, and the occurrence of liver metastasis is a significant contributor to mortality among patients diagnosed with CRC. The survival rate of patients with colorectal liver metastasis has significantly increased with the advancement of comprehensive tumor therapy. However, radical surgery remains the key factor. Since there are frequently multiple liver metastases, which are prone to recurrence after surgery, it is crucial to preserve as much liver parenchyma as possible without affecting the prognosis. The issue of surgical margins plays a crucial role in this regard. In this review, we begin by examining the occurrence of positive surgical margins in liver metastases of patients diagnosed with CRC. We aim to define positive margins in hepatic surgery, examine the relationship between margins and prognosis and establish a foundation for future research in this field.

show abstract