Marine based biomaterials: A Marvel in Periodontal Regeneration – A Review

JOHN, MATHEW; SUGUNAN, AMAL; ASWATHY, S; REVU, S D

doi:10.21608/adjc.2022.94504.1133

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…37 Bahan ini telah digunakan karena biokompatibilitas dan kemampuan untuk meningkatkan penyembuhan di bidang kedokteran gigi. 38 Kitosan merupakan salah satu polisakarida yang telah diterapkan dalam bidang drug delivery system dan tissue engineering. Polisakarida yang terbentuk alami membuktikan penggunaan yang aman dalam produk perawatan kesehatan.…”

Section: Scaffold Untuk Perawatan Regeneratif Periodontalunclassified

Chitosan Collagen Hydrogel: A Potential Scaffold Biomaterial for Periodontal Regenerative Treatment

Wijayanti,

Herawati,

Karina

et al. 2024

interdental

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Introduction: Hydrogels are considered a promising scaffold biomaterial for regenerative periodontal treatment. The development of collagen and chitosan based hydrogels can improve the final characteristics of the hydrogel. Review: Collagen and chitosan are the two main materials used to design scaffolds for tissue engineering. Collagen is a material that is often used to develop hydrogels because it has the advantage of high biocompatibility. In the biomedical field, collagen is often used as a drug delivery system. Collagen has weak mechanical strength so other biomaterials are needed for its use. Chitosan material has high biocompatibility and a slow degradation rate. So the combination of these two materials is a strategic choice for making promising biomaterial scaffolds in periodontal regenerative treatment. Conclusion: Chitosan collagen hydrogel is a potential scaffold biomaterial for periodontal regenerative treatment.

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Section: Scaffold Untuk Perawatan Regeneratif Periodontalunclassified

Chitosan Collagen Hydrogel: A Potential Scaffold Biomaterial for Periodontal Regenerative Treatment

Wijayanti,

Herawati,

Karina

et al. 2024

interdental

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“…In this context, the valorisation of wastes is of utmost importance because this potential alternative approach will reduce waste disposal and use natural resources for new materials development, which will increase the economic value of products. Some of these wastes could be utilised for the development of biomaterials such as calcium phosphates (CaPs) [ 16 , 17 , 18 , 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Production of Nano Hydroxyapatite and Mg-Whitlockite from Biowaste-Derived products via Continuous Flow Hydrothermal Synthesis: A Step towards Circular Economy

et al. 2023

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Biowastes from agriculture, sewage, household wastes, and industries comprise promising resources to produce biomaterials while reducing adverse environmental effects. This study focused on utilising waste-derived materials (i.e., eggshells as a calcium source, struvite as a phosphate source, and CH3COOH as dissolution media) to produce value-added products (i.e., calcium phosphates (CaPs) derived from biomaterials) using a continuous flow hydrothermal synthesis route. The prepared materials were characterised via XRD, FEG-SEM, EDX, FTIR, and TEM analysis. Magnesium whitlockite (Mg-WH) and hydroxyapatite (HA) were produced by single-phase or biphasic CaPs by reacting struvite with either calcium nitrate tetrahydrate or an eggshell solution at 200 °C and 350 °C. Rhombohedral-shaped Mg-WH (23–720 nm) along with tube (50–290 nm diameter, 20–71 nm thickness) and/or ellipsoidal morphologies of HA (273–522 nm width) were observed at 350 °C using HNO3 or CH3COOH to prepare the eggshell and struvite solutions, and NH4OH was used as the pH buffer. The Ca/P (atomic%) ratios obtained ranged between 1.3 and 1.7, indicating the formation of Mg-WH and HA. This study showed that eggshells and struvite usage, along with CH3COOH, are promising resources as potential sustainable precursors and dissolution media, respectively, to produce CaPs with varying morphologies.

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Metabolic bone disorders and the promise of marine osteoactive compounds

Carletti,

Gavaia,

Cancela

et al. 2023

Cell. Mol. Life Sci.

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Metabolic bone disorders and associated fragility fractures are major causes of disability and mortality worldwide and place an important financial burden on the global health systems. These disorders result from an unbalance between bone anabolic and resorptive processes and are characterized by different pathophysiological mechanisms. Drugs are available to treat bone metabolic pathologies, but they are either poorly effective or associated with undesired side effects that limit their use. The molecular mechanism underlying the most common metabolic bone disorders, and the availability, efficacy, and limitations of therapeutic options currently available are discussed here. A source for the unmet need of novel drugs to treat metabolic bone disorders is marine organisms, which produce natural osteoactive compounds of high pharmaceutical potential. In this review, we have inventoried the marine osteoactive compounds (MOCs) currently identified and spotted the groups of marine organisms with potential for MOC production. Finally, we briefly examine the availability of in vivo screening and validation tools for the study of MOCs.

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Marine based biomaterials: A Marvel in Periodontal Regeneration – A Review

Cited by 3 publications

References 19 publications

Chitosan Collagen Hydrogel: A Potential Scaffold Biomaterial for Periodontal Regenerative Treatment

Chitosan Collagen Hydrogel: A Potential Scaffold Biomaterial for Periodontal Regenerative Treatment

Production of Nano Hydroxyapatite and Mg-Whitlockite from Biowaste-Derived products via Continuous Flow Hydrothermal Synthesis: A Step towards Circular Economy

Metabolic bone disorders and the promise of marine osteoactive compounds

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