Marjorie Lansing

Abstract

Her academic career was relatively brief-from 1966 through 1986-but her contributions have lasting impact. Marjorie Lansing developed the "gender gap" concept and helped popularize the term with her path-breaking dissertation research that became the basis for Women

The role of TGF-β and Wnt signaling in gastrointestinal stem cells and cancer

“…Owing to its preference for growth inhibition in the intestine, members of the TGF-b signaling pathway are targets for disruption in colorectal carcinogenesis (Fearon and Vogelstein, 1990). Most commonly mutated is TbRII, followed by Smad2 and Smad4 (Grady, 1998;Massague et al, 2000).…”