Marker Assisted Selection (MAS) in Animal Breeding: A Review

Wakchaure, Rajesh; Ganguly, Subha; Praveen, Praveen Kumar; Kumar, Avinash; Sharma, Subhash; Mahajan, Tanvi

doi:10.4172/2157-7609.1000e127

Cited by 75 publications

(45 citation statements)

References 25 publications

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“…In recent years, advances in molecular technology have created a new horizon for the genetic improvement of quantitative traits, particularly disease-resistant traits. The identification of direct or indirect molecular markers for these traits would facilitate the use of markerassisted selection or gene introgression [8].…”

Section: Salmonellosismentioning

confidence: 99%

Genetics of Disease Resistance in Chicken

Dar¹,

Mumtaz²,

AhmadBhat³

et al. 2018

Application of Genetics and Genomics in Poultry Science

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Although poultry industry has gained momentum during the last few decades, there are still various impediments like improper infrastructure, unscientific management and above all various deadly infectious diseases which incur huge economic losses on poultry industry. These diseases include viral diseases like Avian Influenza, Marek's Disease, New Castle disease and bacterial diseases like Colibacillosis, Pasteurellosis and Salmonellosis, etc. Development of disease resistant poultry has been found successful practice over the use of drugs or vaccines for disease control. Studies involving genome wide associations to figure out certain candidate genes that are involved in disease resistance have also been carried out. Single nucleotide polymorphism studies to unveil the mechanisms underlying disease resistance in chicken show that SNPs and other candidate gene approaches play a vital role in providing disease resistance. Also, understanding the genes and biological pathways that confer genetic resistance to various infections will lead towards the development of more resistant commercial poultry flocks or improved vaccines against various diseases. This chapter shall focus on various factors involved in disease resistance in chicken that interact with the pathogen and provide resistance against the pathogen.

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Section: Salmonellosismentioning

confidence: 99%

Genetics of Disease Resistance in Chicken

Dar¹,

Mumtaz²,

AhmadBhat³

et al. 2018

Application of Genetics and Genomics in Poultry Science

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“…The integration of genetic information along with the phenotypic data may help to increase accuracy of selection (Biochard et al, 2016) and hence, reduce generation interval. Marker assisted selection (MAS) is better than conventional selection for low heritability traits and sex limited traits (Wakchaure et al, 2015). Genomic evaluation system for selection of young bull has already been implemented initially, Switzerland, Germany, Australia (Wiggan et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Identification of genetic marker for prolactin gene related to milk yield in pedigreed Sahiwal population

Karuthadurai

Chakravarthy

Kumaresan

et al. 2018

IJAR

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The study was conducted to identify the genetic marker for prolactin gene related to milk yield in pedigreed Sahiwal population. PCR-RFLP was carried out by using Rsa1 restriction endonuclease and revealed three genotypes GG, GA and AA in Sahiwal population. The frequency of G and A allele of Prolactin gene (exon 3) was estimated as 0.575 and 0.425, whereas the frequencies of GG, GA and AA genotypes for Prolactin gene (exon 3) were estimated as 0.45, 0.25 and 0.30, respectively. Regression analysis inferred that, SNP (G55A) of prolactin gene (exon 3) contributed to an increase in the average test day milk yield by 321.5g which was 3.92% of the average test day milk yield. Forty Sahiwal animals (20 families) under Daughter- Dam Design were screened and it was observed that one SNP (G55A) was found in all the nine families (45%) having heterozygous (GA) genotype. Thus, it could be considered as a potential genetic marker for high milk production in Sahiwal population.

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“…In recent years, advances in molecular technology have created a new horizon for the genetic improvement of quantitative traits, particularly disease-resistant traits. The identification of direct or indirect molecular markers for these traits would facilitate the use of marker-assisted selection or gene introgression (Wakchaure et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Immunogenetics applied to control salmonellosis in chicken: a review

Tohidi

Javanmard

Idris

2017

Journal of Applied Animal Research

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Salmonella infection is an important risk to public health, as newly hatched chicks are very sensitive to Salmonella and the infection transfers to humans through contaminated meat and eggs. Vaccination and antibiotic treatment are common strategies to control salmonellosis. However, it is doubtful whether these strategies succeed, because immune functions depend on the activity of several genes. Genetic improvement of the immune system is an effective method to control salmonellosis. There is genetic variation among breeds and individuals inside breeds in terms of resistance to infection. Genes responsible for resistance to disease can be identified through quantitative trait loci and gene expression analysis. High-throughput technologies assist us to detect single nucleotide polymorphisms (SNPs) and to analyse the regulation of several genes simultaneously. By now, several SNPs have been detected in the chicken genome that influence the function of immune genes. Additionally, the expression level of genes varies during infection depending on the breed and age of chicken and environmental conditions. This review summarizes the results of previous studies on the identification of genes and gene regulation during Salmonella infection in chickens.

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Marker Assisted Selection (MAS) in Animal Breeding: A Review

Cited by 75 publications

References 25 publications

Genetics of Disease Resistance in Chicken

Genetics of Disease Resistance in Chicken

Identification of genetic marker for prolactin gene related to milk yield in pedigreed Sahiwal population

Immunogenetics applied to control salmonellosis in chicken: a review

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