Mass bathing events in River Kshipra, Central India- influence on the water quality and the antibiotic susceptibility pattern of commensal E.coli

Purohit, Manju; Diwan, Vishal; Parashar, Vivek; Tamhankar, Ashok J.; Lundborg, Cecilia Stålsby

doi:10.1371/journal.pone.0229664

Cited by 12 publications

(4 citation statements)

References 22 publications

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“…Only ~10% (n = 4) of the studies included in this review analyzed E. coli from a combination of the three dimensions of the One Health approach (i.e., environment, animals, and humans). Refer Table A2 for specific details and a summary of each study [8,11,16,[25][26][27][28][29][30][31][32][33][34][35][36][37][38][40][41][42][43][44][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61]. One Health is a powerful transdisciplinary tool.…”

Section: Discussionmentioning

confidence: 99%

A One Health Review of Community-Acquired Antimicrobial-Resistant Escherichia coli in India

Rajagopal¹,

Chandy

Graham³

2021

IJERPH

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Antimicrobial resistance (AMR) threatens to undermine nearly a century of progress since the first use of antimicrobial compounds. There is an increasing recognition of the links between antimicrobial use and AMR in humans, animals, and the environment (i.e., One Health) and the spread of AMR between these domains and around the globe. This systematic review applies a One Health approach—including humans, animals, and the environment—to characterize AMR in Escherichia coli in India. E. coli is an ideal species because it is readily shared between humans and animals, its transmission can be tracked more easily than anaerobes, it can survive and grow outside of the host environment, and it can mobilize AMR genes more easily than other intestinal bacteria. This review synthesized evidence from 38 studies examining antimicrobial-resistant E. coli (AR-E) across India. Studies of AR-E came from 18 states, isolated from different sample sources: Humans (n = 7), animals (n = 7), the environment (n = 20), and combinations of these categories, defined as interdisciplinary (n = 4). Several studies measured the prevalence of AMR in relation to last-line antimicrobials, including carbapenems (n = 11), third-generation cephalosporins (n = 18), and colistin (n = 4). Most studies included only one dimension of the One Health framework, highlighting the need for more studies that aim to characterize the relationship of AMR across different reservoirs of E. coli.

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Section: Discussionmentioning

confidence: 99%

A One Health Review of Community-Acquired Antimicrobial-Resistant Escherichia coli in India

Rajagopal¹,

Chandy

Graham³

2021

IJERPH

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“…Water samples were processed as described previously ( Purohit et al, 2020 ). Briefly, 10-fold serial dilutions of water samples (10 ml) were prepared in sterile 0.9% normal saline and processed by standard membrane filtration technique using 47 mm in diameter and a pore size of 0.45 μm membrane filters (Merck Millipore, Darmstadt, Germany).…”

Section: Methodsmentioning

confidence: 99%

Detection and characterization of ESBL-producing Escherichia coli and additional co-existence with mcr genes from river water in northern Thailand

Chotinantakul

Chusri

Okada

2022

PeerJ

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Background Extended-spectrum β-lactamase producing Escherichia coli (ESBL-producing E. coli) have emerged, causing human and animal infections worldwide. This study was conducted to investigate the prevalence and molecular genetic features of ESBL-producing and multidrug-resistant (MDR) E. coli in river water. Methods A total of 172 E. coli samples were collected from the Kok River and Kham River in Chiang Rai, Thailand, during a 10-month period (2020–2021). Results We detected 45.3% of E. coli to be MDR. The prevalence of ESBL-producers was 22%. Among those ESBL-producing strains, CTX-M-15 (44.7%) was predominantly found, followed by CTX-M-55 (26.3%), CTX-M-14 (18.4%), and CTX-M-27 (10.5%). The blaTEM-1 and blaTEM-116 genes were found to be co-harbored with the blaCTX-M genes. Mobile elements, i.e., ISEcp1 and Tn3, were observed. Twelve plasmid replicons were found, predominantly being IncF (76.3%) and IncFIB (52.6%). Whole genome sequencing of ten selected isolates revealed the co-existence of ESBL with mcr genes in two ESBL-producing E. coli. A wide diversity of MLST classifications was observed. An mcr-1.1-pap2 gene cassette was found to disrupt the PUF2806 domain-containing gene, while an mcr-3.4 contig on another isolate contained the nimC/nimA-mcr-3.4-dgkA core segment. Discussion In conclusion, our data provides compelling evidence of MDR and ESBL-producing E. coli, co-existing with mcr genes in river water in northern Thailand, which may be disseminated into other environments and so cause increased risks to public health.

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“…Moreover, heavy metal pollution has also been reported from drinking water sources in the state [19]. Various religious activities and associated mass bathing events further add to the pollution problem [20][21][22][23]. Emerging issues, such as the occurrence of antibiotic-resistant bacteria, have also been reported as being traced to illicit discharge of hospital waste in the city [24,25].…”

Section: Introductionmentioning

confidence: 99%

Physicochemical quality monitoring of groundwater for drinking purposes in rural Ujjain, Central India: findings of a 2-year longitudinal study

Singh¹,

Parashar

Kalyanasundaram³

et al. 2021

SN Appl. Sci.

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Rampant use of groundwater for drinking purposes in several parts of the world has raised the concern over its quality. Owing to increasing population, overuse, and pollution of surface water sources, the use of groundwater has increased to considerable extent. Despite this, little attention is paid towards the monitoring of groundwater resources to assess their suitability for drinking purposes. To assess the groundwater quality in rural areas of Ujjain District of Madhya Pradesh, India, in order to check its suitability for drinking purpose, water quality analysis was done at seven time points during the two study years in six villages of Ujjain District, Central India. A total of 868 groundwater samples from 124 households were collected, and standard analytical methods were employed for analysis. Overall groundwater quality of the area is good and qualified for drinking. However, occurrence of high amount of dissolved solids (> 800 mg/L) and hardness (> 400 mg/L) is the issue of concern, as long-term use of such water might result in variety of health ailments, such as kidney stones and atopic dermatitis in children. Regular monitoring and long-term surveillance of drinking water sources are necessary to keep track of the changes occurring in the system.

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Mass bathing events in River Kshipra, Central India- influence on the water quality and the antibiotic susceptibility pattern of commensal E.coli

Cited by 12 publications

References 22 publications

A One Health Review of Community-Acquired Antimicrobial-Resistant Escherichia coli in India

A One Health Review of Community-Acquired Antimicrobial-Resistant Escherichia coli in India

Detection and characterization of ESBL-producing Escherichia coli and additional co-existence with mcr genes from river water in northern Thailand

Physicochemical quality monitoring of groundwater for drinking purposes in rural Ujjain, Central India: findings of a 2-year longitudinal study

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