Masseter muscle fibre changes following reduction of masticatory function

Tsai, Cheng-Yu; Lin, Yung‐Kuo; Su, Bai-Horng; Yang, Liang; Chiu, Wan‐Chun

doi:10.1016/j.ijom.2011.10.016

Cited by 34 publications

(29 citation statements)

References 24 publications

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“…In addition, correlations among bite force, chewing performance, and masticatory muscle thickness (Raadsheer et al, 1999;Muller et al, 2012) have been established, and it is known that masticatory muscle action is influenced by occlusal factors, such as partial edentulism (Bhoyar et al, 2012). Thus, masticatory muscle function can be reduced by severe tooth loss or a soft diet consumption, as typically selected by edentulous patients, leading to muscle atrophy (Tsai et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Mastication Improvement After Partial Implant-supported Prosthesis Use

et al. 2013

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Section: Introductionmentioning

confidence: 99%

Mastication Improvement After Partial Implant-supported Prosthesis Use

et al. 2013

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“…Among the subtypes, the type IIa fibre has a slower contraction speed, smaller contraction force and better anti‐fatigue ability than type IIb fibre. The type IIx biological characters are in between type IIa and type IIb (Tsai et al, ).…”

Section: Discussionmentioning

confidence: 99%

Botulinum neurotoxin effects on masseter muscle fibre in WNIN obese rats—Scanning electron microscope analysis

et al. 2015

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WNIN/Ob obese mutant rats are unique in comparison to similar rodent models of obesity established in the West. The present study is aimed to evaluate the masticatory function and histological changes in masseter muscle fibres treated with botulinum toxin type A (BoNT/A) in WNIN/Ob rats. Twelve WNIN/Ob obese rats and 12 lean rats at 35 days of age were taken and divided into four groups (6 rats in each group): Group-I (WNIN/Ob) and Group-II (lean) rats were injected with BoNT/A (1 unit) into right side of masseter muscle. For control left masseter of both phenotypes was injected with saline. Group-III (WNIN/Ob) and Group-IV (lean) rats were without any treatment. Growth and food intake was monitored daily for 45 days. Rats were euthanized and gross necropsy was carried out to check any abnormalities. Masseter muscles were dissected and mean muscle mass was recorded. Small portion of muscle was stored in 10% formalin for hematoxylin-eosin (H&E) staining and remaining tissue stored in gluteraldehyde for scanning electron microscopy (SEM). There is a significant decrease in the body weights and food intake of BoNT/A treated obese rats. The H&E staining of the masseter muscle in both groups showed normal morphology and orientation. The SEM analysis showed that, fibre size in BoNT/A treated masseter muscle of obese rats increased more than the saline treated side and in control rats. The increase in the muscle fibre size and transition of muscle fibre subtypes may be due to the reduced masticatory function of the masseter muscle. SCANNING 38:396-402, 2016. © 2015 Wiley Periodicals, Inc.

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“…Furthermore, it prevented surgical artifacts such as scar and contracture . BTX injection in the masticatory muscles of rats has been noted to affect craniofacial anthropometric measurements, reduce muscle fibre size and diminish masseter muscle activity . Increased toxin dose resulted in a greater decrease in muscle activity according to electromyography (EMG) analysis …”

Section: Introductionmentioning

confidence: 99%

Effects of masticatory muscle function affected by BTX on maxillofacial bone growth through the sutural modification

Tsai

Wang

Chang

2019

Orthod Craniofacial Res

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Structured Abstract Objectives To evaluate the effect of botulinum toxin type A (BTX)‐induced masticatory muscle hypofunction on the maxillofacial suture bone growth of growing rats. Setting and Sample Population Department of Orthodontics at Taipei Medical University. Forty‐eight male 4‐week‐old Wistar rats were divided into four groups. The N group received injections of normal saline into each of the masseter and temporalis muscles. The M group received injections of normal saline into each of the temporalis muscle and injections of BTX into each of the masseter muscle. The T group received injections of normal saline into each of the masseter muscle and injections of BTX into each of the temporalis muscle. The MT group received injections of BTX into each of the masseter and temporalis muscles. Material & Methods Rats were sacrificed after 42 days of growth. Changes in body and muscle weight were measured. Anthropometric measurements of the maxillary arch, sutural bone mineral density and sutural bone deposition distances were recorded. Statistical comparisons were performed using analysis of variance. Results No significant change in body weight was found across groups. However, significant decreases were observed in muscle weight, anthropometric measurements, sutural bone mineral density and bone apposition distance in the BTX‐injected group. Conclusions Reduced masticatory muscle function in growing rats can affect maxillofacial suture bone growth.

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Masseter muscle fibre changes following reduction of masticatory function

Cited by 34 publications

References 24 publications

Mastication Improvement After Partial Implant-supported Prosthesis Use

Mastication Improvement After Partial Implant-supported Prosthesis Use

Botulinum neurotoxin effects on masseter muscle fibre in WNIN obese rats—Scanning electron microscope analysis

Effects of masticatory muscle function affected by BTX on maxillofacial bone growth through the sutural modification

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