Materials Science and Engineering of Mucin

Ushida, Kiminori; Murata, Takeomi

doi:10.1016/b978-0-444-62615-8.00004-7

Cited by 8 publications

(1 citation statement)

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“…5 e) [ 233 ]. Owing to the difficulty of artificially reproducing mucins by biotechnological methods or chemical synthesis, so far, only mucins extracted from natural sources are available for commercial purposes [ 243 ]. Typically, mucins are known for their structural heterogeneity; however, qniumucins are more homogeneous, and the level of purity achieved during their isolation is high.…”

Section: Chemistry Of Biological Adhesives and Their Biomedical Applicationsmentioning

confidence: 99%

Bio-based and bio-inspired adhesives from animals and plants for biomedical applications

Lutz

Kımna

Casini

et al. 2022

Materials Today Bio

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With the “many-headed” slime mold Physarum polycelphalum having been voted the unicellular organism of the year 2021 by the German Society of Protozoology, we are reminded that a large part of nature's huge variety of life forms is easily overlooked – both by the general public and researchers alike. Indeed, whereas several animals such as mussels or spiders have already inspired many scientists to create novel materials with glue-like properties, there is much more to discover in the flora and fauna. Here, we provide an overview of naturally occurring slimy substances with adhesive properties and categorize them in terms of the main chemical motifs that convey their stickiness, i.e. , carbohydrate-, protein-, and glycoprotein-based biological glues. Furthermore, we highlight selected recent developments in the area of material design and functionalization that aim at making use of such biological compounds for novel applications in medicine – either by conjugating adhesive motifs found in nature to biological or synthetic macromolecules or by synthetically creating (multi-)functional materials, which combine adhesive properties with additional, problem-specific (and sometimes tunable) features.

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Section: Chemistry Of Biological Adhesives and Their Biomedical Applicationsmentioning

confidence: 99%