Maternal risk factors for neonatal acidosis in women with type 1 diabetes

Abstract

INTRODUCTION Type 1 diabetes in the mother is associated with high risk of adverse neonatal outcomes. The most common complications are congenital malformations, premature delivery, fetal macrosomia, and birth injuries. 1,2 In a study by Mimouni et al 3 , over 25% of infants delivered to diabetic women had perinatal asphyxia. Nowadays, due to significant improvements in diabetic and obstetric care, these numbers seem to have been reduced. 4 Attempts should be made to prevent neonatal acidosis, because it is associated with a higher risk of postnatal adverse outcomes including neurological injuries, multiple organ dysfunctions, and increased long-term morbidity and mortality rates. 5,6 The analysis of umbilical artery pH values has been widely adopted in clinical practice. It is

Determinants of adiponectin levels throughout pregnancy in women with type 1 diabetes mellitus

“…1 The optimal control of glucose levels could additionally reduce the risk of other diabetes -associated conditions such as retinopathy, nephropathy, gestational hypertension, and neonatal acidosis. 1,2 Adiponectin is a type of adipose -derived hormone, which plays a significant role in the maintenance of systemic metabolic homeostasis. It has been reported that changes in adiponectin levels during pregnancy are associated with decreased insulin sensitivity; however, their contribution to lipid metabolism is uncertain.…”

Состояние Плода И Новорожденных, Родившихся От Беременных С Сахарным Диабетом 1-Го Типа, В Зависимости От Вида Анестезии При Операции Кесарева Сечения

“…The presence of diabetes mellitus in the mother determines the high risk of developing a newborn syndrome of a child from a mother with diabetes mellitus -up to 94.4%, the presence of diabetic nephropathy is accompanied by this complication in 100% of cases. The use of regional  ВВЕДЕНИЕ Среди всех эндокринных заболеваний сахарный диабет 1-го типа (СД 1) оказывает наиболее неблагоприятное воздействие на течение беременности, приводящее к осложнениям, отрицательно влияющим на внутриутробное развитие плода и адаптационные возможности новорожденного [1, [4][5][6][7]9]. Важным фактором, определяющим состояние новорожденных, является оперативное родоразрешение и метод анестезиологического обеспечения.…”