2023
DOI: 10.3390/v15061320
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Maternal Th17 Profile after Zika Virus Infection Is Involved in Congenital Zika Syndrome Development in Children

Abstract: Brazil is one of the countries that experienced an epidemic of microcephaly and other congenital manifestations related to maternal Zika virus infection which can result in Congenital Zika Syndrome (CZS). Since the Zika virus can modulate the immune system, studying mothers’ and children’s immune profiles become essential to better understanding CZS development. Therefore, we investigated the lymphocyte population profile of children who developed CZS and their mothers’ immune response in this study. The study… Show more

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“…Previous research has examined the link between the cellular immune response in mothers and children and the development of CZS [27,28]. However, the connection between pre-existing humoral immunity in mothers and CZS in their children remains unexplored.…”
Section: Introductionmentioning
confidence: 99%
“…Previous research has examined the link between the cellular immune response in mothers and children and the development of CZS [27,28]. However, the connection between pre-existing humoral immunity in mothers and CZS in their children remains unexplored.…”
Section: Introductionmentioning
confidence: 99%