We study fermionic fields localized on topologically unstable domain walls bounded by strings in a grand unified theory theoretical framework. Particularly, we found that the localized fermionic degrees of freedom, which are up and down quarks as well as charged leptons, are connected to three independent N = 2, d = 1 supersymmetric quantum mechanics algebras. As we demonstrate, these algebras can be combined to form higher order representations of N = 2, d = 1 supersymmetry. Due to the uniform coupling of the domain wall solutions to the down-quarks and leptons, we also show that a higher order N = 2, d = 1 representation of the down-quark-lepton system is invariant under a duality transformation between the couplings. In addition, the two N = 2, d = 1 supersymmetries of the down-quark-lepton system, combine at the coupling unification scale to form an N = 4, d = 1 supersymmetry. Furthermore, we present the various extra geometric and algebraic attributes that the fermionic systems acquire, owing to the underlying N = 2, d = 1 algebras.