Mathematical model and analysis of the soil-transmitted helminth infections with optimal control

Optimal control analysis of a transmission interruption model for the soil-transmitted helminth infections in Kenya

“…This study is among the few modeling works that has considered a mix of key STH interventions with an optimal control analysis ( Lambura et al, 2020 ; Oguntolu et al, 2023 ). The findings of this modeling work are in line with other modeling studies ( Coffeng et al, 2018 ), and epidemiological studies ( Campbell et al, 2014 ; Strunz et al, 2014 ), that have clearly demonstrated the importance of WASH in accelerating the attainment of helminth elimination when implemented alongside MDA intervention.…”

“…The parameters used to compute model solutions are usually estimated from observational or experimental studies ( Grassly and Fraser, 2008 ). However, only a few STH modeling analysis ( Lambura et al, 2020 ; Oguntolu et al, 2023 ), have applied optimal control analysis to an STH transmission model in formulating public health control strategies targeting elimination. Optimization of the existing interventions and tools is necessary as a priority research area in order to maximize the intervention impact and sustainability ( Gwayi-Chore et al, 2022 ).…”