MATLAB as a Tool in Nuclear Medicine Image Processing

Lyra, Maria; Ploussi, Agapi; Georgantzoglou, Antonios

doi:10.5772/19999

Cited by 9 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Done at high speed by a digitizer at the back-end of the software, this enables real-time visualization and microphotography of the sample. CLSM micrographs are 2D arrays or matrices, consisting of a fixed number of elements or “pixels”, each with a particular location ( x and y coordinates, in the plane of the sample) and a fixed intensity value. − The image information is temporarily stored in the computer and displayed on the monitor enabling real-time visualization and microphotography of the sample . The micrographs are typically acquired as a series of optical sections ( Z -stacks or Z -layers, that are perpendicular to the optical axis), which are stacked together and reconstructed to produce a 3D representation of the sample .…”

Section: General Considerations For Confocal Micrograph Acquisition A...mentioning

confidence: 99%

Tools of the Trade: Image Analysis Programs for Confocal Laser-Scanning Microscopy Studies of Biofilms and Considerations for Their Use by Experimental Researchers

Mhade

Kaushik

2023

ACS Omega

View full text Add to dashboard Cite

Confocal laser-scanning microscopy (CLSM) is the bedrock of the microscopic visualization of biofilms. Previous applications of CLSM in biofilm studies have largely focused on observations of bacterial or fungal elements of biofilms, often seen as aggregates or mats of cells. However, the field of biofilm research is moving beyond qualitative observations alone, toward the quantitative analysis of the structural and functional features of biofilms, across clinical, environmental, and laboratory conditions. In recent times, several image analysis programs have been developed to extract and quantify biofilm properties from confocal micrographs. These tools not only vary in their scope and relevance to the specific biofilm features under study but also with respect to the user interface, compatibility with operating systems, and raw image requirements. Understanding these considerations is important when selecting tools for quantitative biofilm analysis, including at the initial experimental stages of image acquisition. In this review, we provide an overview of image analysis programs for confocal micrographs of biofilms, with a focus on tool selection and image acquisition parameters that are relevant for experimental researchers to ensure reliability and compatibility with downstream image processing.

show abstract

Section: General Considerations For Confocal Micrograph Acquisition A...mentioning

confidence: 99%

Tools of the Trade: Image Analysis Programs for Confocal Laser-Scanning Microscopy Studies of Biofilms and Considerations for Their Use by Experimental Researchers

Mhade

Kaushik

2023

ACS Omega

View full text Add to dashboard Cite

show abstract

“…MATLAB is a simplified programming environment developed by the company MathWorks for mathematical purposes in several areas, working with matrices (1). The versatility of this tool comes from the possibility of working using toolboxes, a set of functions that work around a specific objective.…”

Section: Introductionmentioning

confidence: 99%

Aplicação baseada em MATLAB para análise, pós-processamento de imagens e controle de qualidade de imagens de SPECT

Gonçalves

Grecco

Itikawa³

et al. 2022

Rev Bras Fis Med

View full text Add to dashboard Cite

O objetivo deste trabalho é aprimorar a experiência do usuário em um toolkit para pós-processamento de imagens na modalidade SPECT (Tomografia computadorizada por emissão de fóton único), tornando-o também livremente executável para não usuários do MATLAB. O toolkit foi desenvolvido dentro do MATLAB, usando o recurso de desenvolvimento de aplicativos autônomos, MATLAB AppCompiler, e escrito com o ambiente de aplicativos, MATLAB AppDesigner, na versão R2021a. Várias funcionalidades do aplicativo foram corrigidas ou melhoradas (bugs/falhas, problemas de otimização, aperfeiçoamento do layout), além de adicionar novos recursos e executar o aplicativo de forma totalmente independente do MATLAB. Em termos de desempenho, o toolkit tem um consumo de memória gráfica razoável, mesmo para as máquinas com diferentes especificações de sistema. O programa obteve sucesso em sua execução, além de cumprir sua finalidade para com a medicina nuclear, mostrando-se uma aplicação perfeitamente funcional, para máquinas com diferentes especificações de sistema.

show abstract

“…MATLAB is high-level interactive computing language that provides quantitative analysis and visualisation tools which can be used in multiple applications, including the analysis of different nuclear medicine images. 11 The overall aim is to aid interpretation of IBSs in relation to the response of prostate cancer bone metastases to therapy. We outline (1) the development of the code and (2) comparison with a commercially available software programme.…”

Section: Introductionmentioning

confidence: 99%

A novel tool for improving the interpretation of isotope bone scans in metastatic prostate cancer

Alshehri

Osman

Prise

et al. 2020

BJR

View full text Add to dashboard Cite

Objectives: The isotope bone scan (IBS) is the gold-standard imaging modality for detecting skeletal metastases as part of prostate cancer staging. However, its clinical utility for assessing skeletal metastatic burden is limited due to the need for subjective interpretation. We designed and tested a novel custom software tool, the Metastatic Bone Scan Tool (MetsBST), aimed at improving interpretation of IBSs, and compared its performance with that of an established software programme. Methods: We used IBS images from 62 patients diagnosed with prostate cancer and suspected bone metastases to design and implement MetsBST in MATLAB by defining thresholds used to identify the texture and size of metastatic bone lesions. The results of MetsBST were compared with those of the commercially available automated Bone Scan Index (aBSI) with regression analysis. Results: There was strong agreement between the MetsBST and aBSI results (R2 = 0.9189). In a subregional analysis, MetsBST quantified the extent of metastatic disease in multiple bone sites in patients receiving multimodality therapy (radium-223 and external beam radiotherapy) to illustrate the differences in bone metastatic response to different treatments. Conclusion: The results of MetsBST and the commercial software aBSI were highly consistent. MetsBST introduces novel clinical utility by its ability to differentiate between the responses of different bone metastases to multimodality therapies. Advances in knowledge: MetsBST reduces the variability in assessment of tumour burden caused by subjective interpretation. Therefore, it is a useful aid to physicians reporting nuclear medicine scans, and may improve decision-making in the treatment of metastatic prostate cancer.

show abstract

MATLAB as a Tool in Nuclear Medicine Image Processing

Cited by 9 publications

References 10 publications

Tools of the Trade: Image Analysis Programs for Confocal Laser-Scanning Microscopy Studies of Biofilms and Considerations for Their Use by Experimental Researchers

Tools of the Trade: Image Analysis Programs for Confocal Laser-Scanning Microscopy Studies of Biofilms and Considerations for Their Use by Experimental Researchers

Aplicação baseada em MATLAB para análise, pós-processamento de imagens e controle de qualidade de imagens de SPECT

A novel tool for improving the interpretation of isotope bone scans in metastatic prostate cancer

Contact Info

Product

Resources

About