2024
DOI: 10.3390/inorganics12060155
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Matrix Effect on Singlet Oxygen Generation Using Methylene Blue as Photosensitizer

Jianan Xu,
Laurent Bonneviot,
Yannick Guari
et al.

Abstract: Methylene blue (MB) is a well-established and extensively studied photosensitizer for photodynamic therapy (PDT), since it can generate singlet oxygen with a high quantum yield upon irradiation within the phototherapeutic (600–950 nm) window. However, its activity can decrease due to the formation of dimers or higher aggregates, which can take place in an aqueous solution at relatively high concentrations. The incorporation of this molecule into a matrix can avoid this aggregation and increase its activity rel… Show more

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