Maximizing treatment outcome in post-traumatic stress disorder by combining psychotherapy with pharmacotherapy

Marshall, Randall D.; Cloitre, Marylène

doi:10.1007/s11920-000-0078-3

Cited by 25 publications

(21 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…PTSD is associated with significant disability [50]. Many patients with chronic PTSD are not able to function in work and social activities, and they remained impaired despite maintenance treatment [51]. Our study demonstrates that primary care patients who screen positive for PTSD also experience significant disability in health, social and family functioning even after adjusting for the presence of exposure to trauma both before and during 9/11 and for other mental disorders.…”

Section: Discussionmentioning

confidence: 76%

Posttraumatic stress disorder in primary care one year after the 9/11 attacks

Neria

Gross

Olfson

et al. 2006

General Hospital Psychiatry

Self Cite

View full text Add to dashboard Cite

Objective-To screen for posttraumatic stress disorder (PTSD) in primary care patients 7-16 months after 9/11 attacks and to examine its comorbidity, clinical presentation and relationships with mental health treatment and service utilization.Method-A systematic sample (n = 930) of adult primary care patients who were seeking primary care at an urban general medicine clinic were interviewed using the PTSD Checklist: the Primary Care Evaluation of Mental Disorders (PRIME-MD) Patient Health Questionnaire and the Medical Outcome Study 12-Item Short Form Health Survey (SF-12). Health care utilization data were obtained by a cross linkage to the administrative computerized database.Results-Prevalence estimates of current 9/11-related probable PTSD ranged from 4.7% (based on a cutoff PCL-C score of 50 and over) to 10.2% (based on the DSM-IV criteria). A comorbid mental disorder was more common among patients with PTSD than patients without PTSD (80% vs. 30%). Patients with PTSD were more functionally impaired and reported increased use of mental health medication as compared to patients without PTSD (70% vs. 18%). Among patients with PTSD there was no increase in hospital and emergency room (ER) admissions or outpatient care during the first year after the attacks. Conclusions-In an urban general medicine setting, 1 year after 9/11, the frequency of probable PTSD appears to be common and clinically significant. These results suggest an unmet need for mental health care in this clinical population and are especially important in view of available treatments for PTSD. NIH Public Access

show abstract

Section: Discussionmentioning

confidence: 76%

Posttraumatic stress disorder in primary care one year after the 9/11 attacks

Neria

Gross

Olfson

et al. 2006

General Hospital Psychiatry

Self Cite

View full text Add to dashboard Cite

show abstract

“…It remains contrary to an intuitive clinical lore, some earlier recommendations (Marshall & Cloitre, 2000), and newer studies (Schneier et al, 2012) and to data on combined treatments in other than PTSD mental disorders (see : Cuijpers, 2014).…”

Section: Combined Treatment Compared To Monotherapiesmentioning

confidence: 85%

Prolonged exposure, paroxetine and the combination in the treatment of PTSD following a motor vehicle accident. A randomized clinical trial – The “TRAKT” study

Popiel

Zawadzki

Pragłowska

et al. 2015

Journal of Behavior Therapy and Experimental Psychiatry

View full text Add to dashboard Cite

“…Debido a que existen datos contradictorios acerca de los resultados de las terapias farmacológicas con SSRIs, no existen muchos reportes que indiquen con precisión la interacción de la aplicación conjunta de tratamientos farmacológicos y psicoterapéuticos (Marshall & Cloitre, 2000;Pratchett, Daly, Bierer & Yehuda, 2011;Sonne, Carlsson, Elklit, Mortensen & Ekstrom, 2013). Sin embargo, hasta el momento, no ha sido posible reducir completamente los efectos secundarios asociados a las dosis y a la eventual tolerancia que pueden generar los tratamientos farmacológicos.…”

Section: Abordaje Farmacológicounclassified

Efectos del estrés sobre los procesos de plasticidad y neurogénesis: una revisión

Zarate¹,

Parra²,

Acevedo-Triana

et al. 2014

Univ Psychol

View full text Add to dashboard Cite

r e S u M e n Grandes esfuerzos han sido llevados a cabo para entender los componentes psicobiológicos del estrés y de algunas de las psicopatologías relacionadas con él, tales como los trastornos de ansiedad (ansiedad generalizada o crisis de pánico) e incluso la depresión. Existen evidencias de que procesos como la neurogénesis y la plasticidad se ven enormemente afectados por muchos factores, entre ellos el estrés. En esta revisión se presentan algunos de los principales conceptos sobre la relación entre estrés, plasticidad y neurogé-nesis, a los que se ha llegado a partir de investigaciones realizadas -principalmente en modelos animales-, desde hace algunas décadas. Se realizará una diferenciación entre los efectos ocasionados por estrés crónico y agudo, tratando de establecer las interacciones que sobre estos efectos ejercen algunas variables tales como el género o el rango de edad, se enfatizarán los efectos comportamentales para finalmente revisar algunas de las formas de intervención actualmente más usadas para el tratamiento del estrés. Palabras clave estrés; plasticidad; neurogénesis a B S t r a C tThere is a growing interest in the comprehension of psychobiological mechanisms underlying stress and its relationships with many psychopathologies such as anxiety (i.e. generalized anxiety and panic attacks) or depression. There are several reports on the effects of stress on neurogenesis and plasticity. This review will discuss some of the core concepts on the relation between stress, plasticity and neurogenesis obtained during the last decades from research -mainly based in the use of animal models. The distinguishable effects between acute and chronic stress will also be discussed in relation to other factors as genre and age with an emphasis on behavioral effects. Some current therapeutic approaches will be reviewed as well.

show abstract

Maximizing treatment outcome in post-traumatic stress disorder by combining psychotherapy with pharmacotherapy

Cited by 25 publications

References 35 publications

Posttraumatic stress disorder in primary care one year after the 9/11 attacks

Posttraumatic stress disorder in primary care one year after the 9/11 attacks

Prolonged exposure, paroxetine and the combination in the treatment of PTSD following a motor vehicle accident. A randomized clinical trial – The “TRAKT” study

Efectos del estrés sobre los procesos de plasticidad y neurogénesis: una revisión

Contact Info

Product

Resources

About