MCPD esters and glycidyl esters in food supplements of fish oils, algae oils, and krill oils

Beekmann, Karsten; Sloot, S.J.; Oey, Sergio B.; Leeuwen, S.P.J. van

doi:10.1016/j.foodcont.2022.108865

Cited by 10 publications

(3 citation statements)

References 19 publications

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“…These compounds are present in foods predominantly chemically bound to fatty acids (MCPD and glycidyl esters). However, upon entering the gastrointestinal tract, they readily hydrolyse into free compounds due to gut lipase activity (Beekmann et al, 2022). MCPD and GLY content in processed food is dependent on temperature, time and type of oil/fat; plant-originating fats have higher concentrations.…”

Section: -Monochloropropane-13-diolmentioning

confidence: 99%

Performance Evaluation of the ISO 18363-4:2021 Method for Quantitative Determination of Chloropropanediols and Glycidol in Fats and Oils by GC-MS/MS

Stefanović,

Janković,

Borjan

et al. 2023

Meat Technology

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A new GC-MS/MS method from the ISO 18363 series of standards for determination of fatty acid bound chloropropanediols and glycidol was assessed for its performance characteristics. This method enables indirect simultaneous determination of free 2-monochloropropane-1,3-diol (2-MCPD), 3-monochloropropane-1,2-diol (3-MCPD) and glycidol in a single sample preparation and analysis protocol. Results of the validation study show satisfactory performance characteristics, well within required limits. Recently held proficiency testing also showed the adequate performance of the laboratories employing this method. Taking into consideration the simpler sample preparation and stringent quality control inherent to this protocol, wider use of ISO 18363:4:2021 for routine applications can be expected in the foreseeable future.

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Section: -Monochloropropane-13-diolmentioning

confidence: 99%

Performance Evaluation of the ISO 18363-4:2021 Method for Quantitative Determination of Chloropropanediols and Glycidol in Fats and Oils by GC-MS/MS

Stefanović,

Janković,

Borjan

et al. 2023

Meat Technology

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“…The nephrotoxicity of 3-MCPDE is due to the inhibition of glycolysis during the metabolism of 3-MCPD to β-chlorolactic acid. 63 In addition, the increase in oxalate can also lead to renal damage. 64 Oxidative stress is a negative effect produced by free radicals in the body.…”

Section: Institute and Authormentioning

confidence: 99%

“…Thus, galactoglycerin in urine can be considered as an early biomarker for the influence of 3-MCPD on the kidney. The nephrotoxicity of 3-MCPDE is due to the inhibition of glycolysis during the metabolism of 3-MCPD to β-chlorolactic acid . In addition, the increase in oxalate can also lead to renal damage …”

Section: Hot Research Topics On 3-mcpdementioning

confidence: 99%

Bibliometric Analysis of Research Trends on 3-Monochloropropane-1,2-Diol Esters in Foods

Wei

Liu

Zheng

et al. 2022

J. Agric. Food Chem.

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3-Monochloropropane-1,2-diol esters (3-MCPDE) are common food contaminants mainly formed in the edible oil refining process. Due to their potential hazards, 3-MCPDE has become a widespread food safety concern. In this study, CiteSpace and VOSviewer were used to conduct a bibliometric analysis on the 3-MCPDE research papers collected in the Web of Science Core Collection from 1998 to 2022. The results showed that the number of research publications on 3-MCPDE has increased rapidly since 2010. Analysis of the hotspots in 3-MCPDE studies showed that more attention has been paid to the exposure assessment, formation mechanism, detection methods, mitigation methods and toxicity, and toxicology of 3-MCPDE. Finally, the future trends of research on 3-MCPDE were analyzed and proposed. The mitigation methods and toxicology studies of 3-MCPDE are still the research hotspots in the future. In addition, nutritional intervention for 3-MCPDE toxicity will be an emerging trend.

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Food processing contaminants: Dietary exposure to 3-MCPD and glycidol and associated burden of disease for Italian consumers

Mihalache

Dall’Asta

2023

Environmental Research

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MCPD esters and glycidyl esters in food supplements of fish oils, algae oils, and krill oils

Cited by 10 publications

References 19 publications

Performance Evaluation of the ISO 18363-4:2021 Method for Quantitative Determination of Chloropropanediols and Glycidol in Fats and Oils by GC-MS/MS

Performance Evaluation of the ISO 18363-4:2021 Method for Quantitative Determination of Chloropropanediols and Glycidol in Fats and Oils by GC-MS/MS

Bibliometric Analysis of Research Trends on 3-Monochloropropane-1,2-Diol Esters in Foods

Food processing contaminants: Dietary exposure to 3-MCPD and glycidol and associated burden of disease for Italian consumers

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