2016
DOI: 10.1016/j.ijbiomac.2016.01.062
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Mcy protein, a potential antidiabetic agent: evaluation of carbohydrate metabolic enzymes and antioxidant status

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Cited by 12 publications
(6 citation statements)
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References 32 publications
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“…Our investigations on enzyme inhibition coincide with that of Marella et al (2016) where the Mcy protein, a potent antidiabetic active principle , inhibited the AR and AG enzymes in in vitro studies. As the concentration of NEA increased, the percentage of inhibition was concomitantly improved.…”
Section: In Vitro α-Glucosidase Inhibition Assay and Aldose Reductase Inhibition Assaysupporting
confidence: 75%
“…Our investigations on enzyme inhibition coincide with that of Marella et al (2016) where the Mcy protein, a potent antidiabetic active principle , inhibited the AR and AG enzymes in in vitro studies. As the concentration of NEA increased, the percentage of inhibition was concomitantly improved.…”
Section: In Vitro α-Glucosidase Inhibition Assay and Aldose Reductase Inhibition Assaysupporting
confidence: 75%
“…Protein from Momordica cymbalaria Hook. f. showed in vitro enzyme inhibition which decreases glucose production, improve carbohydrate metabolism in animal studies (Marella et al 2016).…”
Section: Fruits Hypoglycemicmentioning
confidence: 99%
“…This principle lowered the fasting plasma glucose level in normoglycemic and hyperglycemic rats [Singh and Chandra, 1977] Fruits, Seeds The protein named Mcy isolated from the fruits and seeds of M. cymbalaria lowered the fasting plasma glucose levels in streptozotocin-induced diabetic rats [Rajasekhar et al, 2010]. It also exhibited good antihyperlipidemic action [Marella et al, 2015] and inhibitory actions on aldose reductase and α-glucosidase activities [Marella et al, 2016]…”
Section: Seedsmentioning
confidence: 99%
“…The supernatant is collected, the pellets were re-extracted and the supernatants were pooled. Proteins in the supernatant are then precipitated with 5 volumes (V/V) of 100% acetone and incubated at -20°C for 2 h. After centrifugation, the pellet is washed twice with 80% acetone and then resuspended in appropriate buffer (Marella et al 2016).…”
Section: Tris-acetone Extractionmentioning
confidence: 99%