Todd's paralysis is rare phenomenon, but its identification is of key diagnostic and therapeutic value. The authors present a clinical observation of post-traumatic encephalopathy accompanied by Todd's paralysis. The main differential diagnostic criteria for post-traumatic encephalopathy with cerebral paroxysms in the form of Todd's paralysis and stroke syndromes have been identified: closed craniocerebral injury in history; epileptiform paroxysms; a clear connection between epileptic seizures and trauma; characteristic "scarcity" of the clinical picture; stereotype paroxysms and rapid regression of symptoms; electroencephalographic study; absence of significant pathological changes on magnetic resonance tomo- and angiography; dissociation between the presence of a neurological deficit and magnetic resonance neuroimaging data; cumulated clinical analysis.