Measles: Global Indicators and Progress on the road for Achieving and Sustaining Virus Eradication: A Review

Abstract

Measles morbillivirus is regarded as one of the most influential contagious virus in the timeline of human history. Before the classification of this virus and formulation of early vaccines in the starting 1960s, it was responsible for killing 0.1 – 10 % of every birth cohort. While live-attenuated samples of measles morbillivirus have considerably mitigated fatality rate around 99% in developed states, - 1 million fatalities are nevertheless occurring on yearly basis in the developing states, and multiple queries are awaiting response regarding immune-pathogenesis of measles, the vaccines and correlates of immunity itself. This study analyzes the considerable influence of vaccination uptake brought upon the reduction of measles disease burden all over the world, the foundation of effective vaccines along with their effectiveness and safety profiles, worldwide scenario of vaccination, the economic potential of investment in effective vaccines, the multiple impediments observed in control of measles in modern years, along with the major issues that have to be tackled for achieving a planet free from measles.