The COVID‐19 pandemic imposed unparalleled challenges for the chemical industry, leading to disruptions in supply chains and demand dynamics. This period of crisis tested the adaptability and resilience of global chemical companies. Despite the challenges, the chemical industry exhibited remarkable innovation, collaboration, and adaptability. It demonstrated its capacity to respond swiftly and effectively to societal needs. Key lessons emerged, emphasizing the importance of diversifying supply chains, implementing scenario planning, and embracing digitalization for enhanced preparedness. As the world progresses toward recovery, the chemical industry is poised to leverage the valuable lessons learned. Industry 4.0 adoption, agile decision‐making, and collaborative efforts with various sectors, research institutions, and governments have accelerated digital transformation and enabled collective responses to global challenges. By focusing on healthcare, advanced materials, and circular economy initiatives, the industry can align with market trends and contribute to societal needs. Furthermore, prioritizing sustainability, regionalization, and responsible practices will be integral to future success. Proactive measures such as strengthening supply chain resilience, enhancing digital capabilities, and fostering a culture of innovation will empower chemical companies to navigate future challenges with confidence. By investing in sustainability, employee well‐being, and responsible practices, the chemical industry can play a pivotal role in building a more resilient and sustainable world. © 2023 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).