Measuring Deterioration in International Classification of Functioning Domains of People With Multiple Sclerosis Who Are Ambulatory

Paltamaa, Jaana; Sarasoja, Taneli; Leskinen, Esko; Wikström, Juhani; Mälkiä, Esko

doi:10.2522/ptj.20070064

Cited by 101 publications

(99 citation statements)

References 44 publications

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“…6MWT distance is significantly reduced in persons with MS, which suggests that they are at risk for mortality and impaired mobility. 24,28,29 What This Study Adds This study reports on clinical characteristics and physical performance measures related to 6MWT as alternative methods to explain risk of disablement. Performance on the 6MWT, FST, and ABC scale is influenced by age and disability in persons with MS.…”

Section: Key Messages What Is Already Known On This Topicmentioning

confidence: 99%

“…13,34 The 6MWT test has high reliability (ICC: 0.95-0.99) in persons with MS 34 and is responsive to changes in deteriorating status in persons with MS. 29 A single repetition of the 6MWT was deemed appropriate, both in order to avoid participant fatigue and because a single repetition of the 6MWT was previously determined to be reliable in the MS population. 34 Subjects were instructed to walk as quickly and safely as possible for 6 minutes.…”

Section: The 6-minute Walk Testmentioning

confidence: 99%

“…19 Performance on the 6MWT is significantly reduced in persons with MS, which may suggest an increased risk of mortality and limited mobility. 24,28,29 A reduced distance on the 6MWT has predicted increased risk of morbidity and mortality in several patient populations. 13,[24][25][26][27] Therefore, identifying factors that influence 6MWT performance in persons with MS is important.…”

Section: Introductionmentioning

confidence: 99%

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Six-Minute Walk Test for Persons with Mild or Moderate Disability from Multiple Sclerosis: Performance and Explanatory Factors

Wetzel¹,

Fry²,

Pfalzer³

2011

Physiotherapy Canada

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Purpose: The primary purpose of this study was to determine the extent to which health factors, functional measures, and pulmonary impairment explain performance on 6-Minute Walk Test (6MWT) distance in ambulatory persons with multiple sclerosis (MS). Another purpose was to determine the effect of disability and age on 6MWT performance and explanatory factors. Methods: A cross-sectional study design was used to evaluate factors that explain performance on the 6MWT in 64 community-dwelling persons with MSrelated disability (Expanded Disability Status Scale [EDSS] 3.8 e 1.6). Of the 64 participants, 43 (67.2%) exhibited mild disability (EDSS <4.0) and 21 (32.8%) had moderate disability Results: EDSS, ABC, FST, SST, BAL, MVV, MIP, and MEP were significantly associated with 6MWT distance after adjusting for age. Multiple step-wise linear regression analysis revealed that ABC, FST, and BAL were significant and independent explanatory factors of 6MWT distance. ABC and FST explained 75% of the variance in 6MWT performance (R 2 ¼ 0.75). Curvilinear regression analysis revealed that the FST is the most significant explanatory factor for 6MWT distance, explaining 79% of the variance (R 2 ¼ 0.79). Conclusions: 6MWT performance in persons with MS was explained by balance confidence (ABC) and stair-climbing ability (FST). The ABC and FST may be practical clinical measures for explaining walking ability and determining risk for disablement in persons with MS. RÉ SUMÉObjectif : L'objectif principal de cette é tude é tait de dé terminer jusqu'à quel point les facteurs de santé , les mesures fonctionnelles et les incapacité s pulmonaires influent sur les ré sultats en terme de distance au test de marche de 6 minutes (6MWT) chez les personnes qui souffrent de sclé rose en plaques (SP) et qui sont encore ambulatoires. Un autre objectif consistait à é valuer l'effet de l'incapacité et de l'â ge sur les ré sultats au 6MWT et sur les facteurs explicatifs. Mé thode : Une é tude transversale a é té utilisé e pour é valuer les facteurs expliquant les ré sultats au 6MWT chez 64 personnes avec SP qui vivent dans des habitations communautaires, avec incapacité s lié es à leur maladie (é chelle d'incapacité EDSS 3,8 e 1,6). Au total, 43 sujets (67,2 %) dé montraient une incapacité lé gè re (EDSS < 4,0) et 21 (32,8 %) avaient une incapacité modé ré e (EDSS 4,0-6,5). The authors have no conflicts of interest to declare.We thank the following individuals for their assistance with the study: Susan Kushner, PT, MS; Anang Chokshi, DPT; Shelley Wagner, DPT; Emily Jackson, DPT; Julie Vasieck, DPT; Shawna Pringle, DPT; and Angela English, DPT. Jane L. Wetzel, PT, PhD: Associate Professor, Department of Physical Therapy, Youngstown State University, Youngstown, Ohio (current); Duquesne University, Pittsburgh, Pennsylvania (at time of study). Ré sultats : Les tests EDSS, ABC, FST, SST, BAL, MVV, MIP et MEP é taient associé s de maniè re significative à la distance parcourue lors du 6MWT, aprè s ajustement de l'â ge. Une analyse de ré gressio...

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Section: Key Messages What Is Already Known On This Topicmentioning

confidence: 99%

Section: The 6-minute Walk Testmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Six-Minute Walk Test for Persons with Mild or Moderate Disability from Multiple Sclerosis: Performance and Explanatory Factors

Wetzel¹,

Fry²,

Pfalzer³

2011

Physiotherapy Canada

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“…A total of 47 papers described the use of ICF in the contexts of a specific health condition, the most frequent being stroke [439,469,470,472,473], multiple sclerosis [444,464,465,467,477], rheumatoid arthritis [440,443,449,454,474], traumatic brain injury [455,457,459] and HIV/AIDS [441,446,447].…”

Section: Clinical Contextsmentioning

confidence: 99%

Systematic literature review on ICF from 2001 to 2009: its use, implementation and operationalisation

Černiauskaitė

Quintas

Boldt

et al. 2010

Disability and Rehabilitation

245

161

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Conclusions. The ICF contributed to the development of research on functioning and on disability in clinical, rehabilitation as well as in several other contexts, such as disability eligibility and employment. Diffusion of ICF research and use in a great variety of fields and scientific journals is a proof that a cultural change and a new conceptualisation of functioning and disability is happening.

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“…Subjects who met the eligibility criteria were ambulatory with no major additional diseases. Of the 120 ambulatory PwMS who volunteered to participate in the physical functioning measures in 2000, 109 attended the follow-up measures in 2002 [26] and 77 completed the follow-up study in 2012. The study design was approved by the Ethics Committee of the Central Finland Health Care District.…”

Section: Participantsmentioning

confidence: 99%

Ten-year follow-up of health-related quality of life among ambulatory persons with multiple sclerosis at baseline

2016

Self Cite

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2 ABSTRACTPurpose: The aim of this 10-year follow-up study was to determine changes in health-related quality of life (HRQoL) over time among ambulatory persons with MS (PwMS) at the baseline using generic and disease-specific instruments. Methods Conclusions:The results of this study suggest that ambulatory PwMS at baseline reported reduced HRQoL in physical functioning after a 10-year follow-up period while emotional well-being was maintained and social functioning improved. The scores in the other HRQoL dimensions and scales remained unchanged. More long-term population-based studies are needed to precisely determine the development of HRQoL among PwMS.

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Measuring Deterioration in International Classification of Functioning Domains of People With Multiple Sclerosis Who Are Ambulatory

Abstract: The results show the relative responsiveness of different measures in the subsample who deteriorated and provide data that can facilitate the interpretation of score changes in people with MS who are ambulatory for future studies and in clinical practice.

Cited by 101 publications

References 44 publications

Six-Minute Walk Test for Persons with Mild or Moderate Disability from Multiple Sclerosis: Performance and Explanatory Factors

Six-Minute Walk Test for Persons with Mild or Moderate Disability from Multiple Sclerosis: Performance and Explanatory Factors

Systematic literature review on ICF from 2001 to 2009: its use, implementation and operationalisation

Ten-year follow-up of health-related quality of life among ambulatory persons with multiple sclerosis at baseline

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