Sustainable decision-making and policies for regional development need clear understanding of future trends in population change. Emigration as one of the core factors of population change causes the greatest uncertainty in the demographic forecasts. Population change due to emigration is bright especially in peripheral regions what strengthens their unfavourable socio-economic conditions. Within the present study, the authors forecast population change due to emigration in peripheral region with high emigration rates. The authors offer three scenarios – current, half of current, and zero emigration, which demonstrate how differentiated population change due to emigration may be in case of different suppositions. Such approach focuses on the issue at local level. For numerical expression of population change, the authors apply simulation model based on system dynamics methods. Forecast results of future population change due to emigration in each scenario may be as a basis for timely inclusion of issues in regional development policies.