2024
DOI: 10.1021/acs.langmuir.4c00958
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Measuring the Transmembrane Registration of Lipid Domains in Droplet Interface Bilayers through Tensiometry

Braydon G. Segars,
Michelle Makhoul-Mansour,
Joyce Beyrouthy
et al.

Abstract: Diverse collections of lipids self-assemble into domains within biological membranes, and these domains are typically organized in both the transverse and lateral directions of the membrane. The ability of the membrane to link these domains across the membrane's interior grants cells control over features on the external cellular surface. Numerous hypothesized factors drive the cross-membrane (or transverse) coupling of lipid domains. In this work we seek to isolate these transverse lipid−lipid influences in a… Show more

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