Mechanical Left Ventricular Dyssynchrony in Heart Failure Patients With Narrow QRS Duration as Assessed by Three-Dimensional Speckle Area Tracking Strain

Tatsumi, Kazuhiro; Tanaka, Hidekazu; Matsumoto, Kensuke; Hiraishi, Mana; Miyoshi, Tatsuya; Tsuji, Takayuki; Kaneko, Akira; Ryo, Keiko; Yamawaki, Kohei; Fukuda, Yuko; Norisada, Kazuko; Onishi, Tetsuari; Kawai, Hiroya; Hirata, Ken‐ichi

doi:10.1016/j.amjcard.2011.05.015

Cited by 20 publications

(13 citation statements)

References 27 publications

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“…Furthermore, the prevalence of significant ASDI in heart failure patients with narrow QRS was significantly higher than in normal controls (22 vs. 0%, P = 0.01) but significantly lower than in heart failure patients with wide QRS (22 vs. 59%, P < 0.01). These observations suggest that the use of 3D speckle area tracking strain might be extended to heart failure patients with narrow QRS who may be potential candidates for CRT …”

Section: De Speckle Tracking Assessment Of LV Mechanical Dyssynchronymentioning

confidence: 96%

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Left Ventricular Dyssynchrony by Three‐Dimensional Echocardiography: Current Understanding and Potential Future Clinical Applications

Cai

Ahmad

2015

Echocardiography

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Left ventricular mechanical dyssynchrony is an important prognostic factor for patients with symptomatic systolic heart failure and has emerged as a therapeutic target for cardiac resynchronization therapy (CRT). However, approximately one-third of patients fail to improve after CRT based on current guideline recommendations and electrocardiographic criteria. Two-dimensional echocardiography and tissue Doppler-based techniques have shown variable results in assessment of left ventricular (LV) dyssynchrony and have limited value in clinical practice. Three-dimensional echocardiography (3DE) is an appealing novel imaging modality that has been recently used in quantitative evaluation of global and regional LV function. There is accumulating evidence that 3DE measurement of LV systolic dyssynchrony index may potentially play a role in predicting the short- and long-term response to CRT and further improve patient selection for CRT. New developments in 3DE speckle tracking technique and strain analysis may further improve the accuracy of LV mechanical dyssynchrony assessment in this population. In addition, recent studies suggest that mechanical dyssynchrony is present in patients with LV hypertrophy and diastolic heart failure. Three-dimensional echocardiographic assessment of dyssynchrony may aid in diagnosis and in predicting long-term outcome in these patients. We will summarize current understanding of 3DE techniques and parameters in assessment of LV mechanical dyssynchrony in the population of patients with systolic heart failure, LV hypertrophy, and diastolic heart failure. A number of the novel 3DE techniques described in this review are early in their stage of development, and they will continue to evolve and need further testing in large multicenter studies.

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Section: De Speckle Tracking Assessment Of LV Mechanical Dyssynchronymentioning

confidence: 96%

“…Tatsumi et al . assessed whether heart failure patients with narrow QRS have mechanical LV dyssynchrony.…”

Section: De Speckle Tracking Assessment Of LV Mechanical Dyssynchronymentioning

confidence: 99%

Left Ventricular Dyssynchrony by Three‐Dimensional Echocardiography: Current Understanding and Potential Future Clinical Applications

Cai

Ahmad

2015

Echocardiography

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“…According to the inclusion criteria, 7 case-control studies [21][22][23][24][25][26][27] were included in this meta-analysis, and 88 studies were excluded. The publication years of the involved studies ranged from 2010 to 2012.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Quantitative Assessment of Left Ventricular Function by 3‐Dimensional Speckle‐Tracking Echocardiography in Patients With Chronic Heart Failure

Jiang

Jun

et al. 2014

J of Ultrasound Medicine

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“…The assessment of remaining LV regional contractility is lacking [11]. In a small study, 3D strain dyssynchrony index, (area tracking approach using the average difference between peak and end-systolic area strain, derived from 16 LV segments), was proposed for predicting CRT-response [13]. An integrative approach of dyssynchrony and function, using a new longitudinal strain integral-derived method, has appeared more relevant [29, 37].…”

Section: Discussionmentioning

confidence: 99%

“…In a further advancement, 3D speckle-tracking echocardiography (STE) has been proposed as an alternative and potentially more accurate method for quantifying LVMD and for identifying patients suitable for CRT [11–13]. …”

Section: Introductionmentioning

confidence: 99%

Pilot study using 3D–longitudinal strain computation in a multi-parametric approach for best selecting responders to cardiac resynchronization therapy

Fournet¹,

Bernard²,

Maréchaux³

et al. 2017

Cardiovasc Ultrasound

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BackgroundAlmost all attempts to improve patient selection for cardiac resynchronization therapy (CRT) using echo-derived indices have failed so far. We sought to assess: the performance of homemade software for the automatic quantification of integral 3D regional longitudinal strain curves exploring left ventricular (LV) mechanics and the potential value of this tool to predict CRT response.MethodsForty-eight heart failure patients in sinus rhythm, referred for CRT-implantation (mean age: 65 years; LV-ejection fraction: 26%; QRS-duration: 160 milliseconds) were prospectively explored. Thirty-four patients (71%) had positive responses, defined as an LV end-systolic volume decrease ≥15% at 6-months. 3D–longitudinal strain curves were exported for analysis using custom-made algorithms. The integrals of the longitudinal strain signals (IL,peak) were automatically measured and calculated for all 17 LV-segments.ResultsThe standard deviation of longitudinal strain peak (SDIL,peak) for all 17 LV-segments was greater in CRT responders than non-responders (1.18% s−1 [0.96; 1.35] versus 0.83% s−1 [0.55; 0.99], p = 0.007). The optimal cut-off value of SDIL,peak to predict response was 1.037%.s−1. In the 18-patients without septal flash, SDIL,peak was significantly higher in the CRT-responders.ConclusionsThis new automatic software for analyzing 3D longitudinal strain curves is avoiding previous limitations of imaging techniques for assessing dyssynchrony and then its value will have to be tested in a large group of patients.

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Mechanical Left Ventricular Dyssynchrony in Heart Failure Patients With Narrow QRS Duration as Assessed by Three-Dimensional Speckle Area Tracking Strain

Cited by 20 publications

References 27 publications

Left Ventricular Dyssynchrony by Three‐Dimensional Echocardiography: Current Understanding and Potential Future Clinical Applications

Left Ventricular Dyssynchrony by Three‐Dimensional Echocardiography: Current Understanding and Potential Future Clinical Applications

Quantitative Assessment of Left Ventricular Function by 3‐Dimensional Speckle‐Tracking Echocardiography in Patients With Chronic Heart Failure

Pilot study using 3D–longitudinal strain computation in a multi-parametric approach for best selecting responders to cardiac resynchronization therapy

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