MERGULHÃO, Marcello V. Laser powder bed fusion of Co-Cr-Mo alloy: mechanical properties and microstructure after heat treatment. 2022. 154 p. Tese (Doutorado em Tecnologia Nuclear) -Instituto de Pesquisas Energéticas e Nucleares -IPEN-CNEN/SP. São Paulo. Powder bed fusion by laser (PBF-L) stands out among the main processes of additive manufacturing (AM) for manufacturing parts with highly complex geometry and weight relief, specially in the aerospace and biomedical industries. The adequacy of the PBF-L process parameters and the performance of post-processing by heat treatments are fundamental to ensure the quality and optimize the useful life of medical prostheses and implants. Manufacturing Co-Cr-Mo alloys by PBF-L are the focus of recurrent research because they have great potential in the fabrication of customized medical and dental prostheses. So far, previous studies emphasize the optimization of macroscopic properties, such as aging behavior. In Co-Cr-Mo alloys there are few literatures covering the processing window and its relationship with the microstructural and mechanical characteristics. This work presents an investigation of the main parameters of the PBF-L process in a standardized Co-Cr-Mo alloy ASTM F75 through the effects and influences of laser additive manufacturing through mechanical analysis and microstructure obtained in the samples.Additionally, heat treatment by solubilization was carried out in the PBF-L Co-Cr-Mo alloy processed. The analyzes obtained were compared with the conventional precision casting route. The results obtained allowed to determine the appropriate FLP-L process parameters for the Co-Cr-Mo alloy, allowing a microstructure with no defects, obtaining densifications higher than 99%. The investigated process-property relationships are important to define the influence of the analyzed parameters in the processing and can support the establishment of protocols in the standardization of the Co-Cr-Mo alloy FLP-L process.