Mechanisms of sinus node cycle length changes during ventricular fibrillation

Wasmund, Stephen L.; Pacchia, Christina F.; Page, Richard L.; Hamdan, Mohamed H.

doi:10.1007/s10286-015-0319-5

Cited by 1 publication

(2 citation statements)

References 9 publications

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“…The initial search led to the identification of 975 studies, among which 855 were considered potentially relevant based on the title and abstract. Twenty-nine potentially relevant studies were retrieved for detailed analysis 8,11,18–34. Only 10 articles met the eligibility criteria 9,35–43…”

Section: Resultsmentioning

confidence: 99%

“…More recently, IMT has been evaluated as an adjunct therapy to improve autonomic modulation due to the recognized respiratory effects. According to several studies, IMT may reduce sympathetic activity9,11 through respiratory muscle metaboreflex attenuation,12 improving functional capacity and physical performance 12–15. Therefore, the purpose of this study was to systematically review the effects of the IMT on global cardiovascular function through autonomic function modulation of heart rate variability (HRV) and arterial blood pressure.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Current insights of inspiratory muscle training on the cardiovascular system: a systematic review with meta-analysis</p>

Cipriano¹,

Júnior²,

Santos³

et al. 2019

IBPC

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Background: Cardiorespiratory limitation is a common hallmark of cardiovascular disease which is a key component of pharmacological and exercise treatments. More recently, inspiratory muscle training (IMT) is becoming an effective complementary treatment with positive effects on muscle strength and exercise capacity. We assessed the effectiveness of IMT on the cardiovascular system through autonomic function modulation via heart rate variability and arterial blood pressure. Methods: Randomized controlled trials (RCTs) were identified from searches of The Cochrane Library, MEDLINE and EMBASE to November 2018. Citations, conference proceedings and previous reviews were included without population restriction, comparing IMT intervention to no treatment, placebo or active control. Results: We identified 10 RCTs involving 267 subjects (mean age range 51–71 years). IMT programs targeted maximum inspiratory pressure (MIP) and cardiovascular outcomes, using low ( n =6) and moderate to high intensity ( n =4) protocols, but the protocols varied considerably (duration: 1–12 weeks, frequency: 3–14 times/week, time: 10–30 mins). An overall increase of the MIP (cmH 2 O) was observed (−27.57 95% CI −18.48, −37.45, I 2 =64%), according to weighted mean difference (95%CI), and was accompanied by a reduction of the low to high frequency ratio (−0.72 95% CI−1.40, −0.05, I 2 =50%). In a subgroup analysis, low- and moderate-intensity IMT treatment was associated with a reduction of the heart rate (HR) (−7.59 95% CI −13.96, −1.22 bpm, I 2 =0%) and diastolic blood pressure (DBP) (−8.29 [−11.64, −4.94 mmHg], I 2 =0%), respectively. Conclusion: IMT is an effective treatment for inspiratory muscle weakness in several populations and could be considered as a complementary treatment to improve the cardiovascular system, mainly HR and DBP. Further research is required to better understand the above findings.

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