Mechanochemical synthesis and properties of fullerene derivatives

Muradyan, V. E.; Арбузов, А. А.; Smirnov, Yu. M.; Lesnichaya, V. A.

doi:10.1134/s1070363211080159

Cited by 4 publications

(9 citation statements)

References 3 publications

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“…Meanwhile, only a small amount of alkali in comparison to the method reported before is required as a catalyst to avoid the use of excessive hydroxylation reagent. [ 39,41–43 ] Furthermore, synthetic conditions of fullerenols are optimized (Table S1, Supporting Information, Figure 1b–e, Figure S1–S5, Supporting Information) by exploring the influence of the amount of catalyst NaOH and hydroxylation reagent H 2 O 2 and lapping ways in the process of synthesis on the molecular structure and yield of as‐prepared fullerenol products with qualitative and quantitative characterization (details are listed at the additional discussion of supporting information). Finally, it was chosen as the optimized synthetic conditions that the C 60 to NaOH mass ratio of 10:1, the C 60 to H 2 O 2 molar ratio of 0.139:2, and mechanical ball milling at a speed of 300 rpm, to prepare moderate hydroxyl number fullerenols C 60 (OH) 20 with good water solubility.…”

Section: Resultsmentioning

confidence: 99%

Eco‐Friendly and Scalable Synthesis of Fullerenols with High Free Radical Scavenging Ability for Skin Radioprotection

Zhao

Wang

Xie

et al. 2021

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Radiation dermatitis is a common but torturous side effect during radiotherapy, which greatly decreases the life quality of patients and potentially results in detrimental cessation of tumor treatment. Fullerenol, known as “free radical sponge,” is a great choice for skin radioprotection because of its broad‐spectrum free radical scavenging performance, good chemical stability, and biosafety. In this work, a facile scalable and eco‐friendly synthetic method of fullerenols by catalyst assistant mechanical chemistry strategy is provided. As no organic solvent or high concentration of acid and alkali is introduced to this synthetic system, large‐scale (>20 g) production of fullerenols with high yield (>95%) is obtained and no complicated purification is required. Then, the skin radioprotective performance of fullerenols is systematically explored for the first time. In vitro results indicate that fullerenols significantly block the reactive oxygen species‐induced damage and enhance the viability of irradiated human keratinocyte cells. In vivo experiments suggest that medical sodium hyaluronate hydrogels loaded with fullerenols are suitable for skin administration and powerfully mitigate radiodermatitis via effectively protecting epidermal stem cells. The work not only provides an efficient gram‐scale and eco‐friendly synthetic method of fullerenols, but also promotes the development of fullerenols as potential skin radioprotectors.

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Section: Resultsmentioning

confidence: 99%

Eco‐Friendly and Scalable Synthesis of Fullerenols with High Free Radical Scavenging Ability for Skin Radioprotection

Zhao

Wang

Xie

et al. 2021

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“…34,36 Nevertheless, when conducting the reaction in air a totally different product was obtained. 96,97 Forty-five milligrams of C 60 with about 250 equiv. of KOH were mixed in a Wig-L-Bug mill in air for 1 h, and then quenched with water, C 60 (OH) n (n = 27.2) was acquired in 84% yield.…”

Section: Oxygenation Of C 60mentioning

confidence: 99%

“…The same reaction in a planetary ball mill for 1 h at 550 rpm afforded fullerenols with an empirical formula of C 60 (OH) 27.6 H 7.1 . 97 Replacing KOH with LiNH 2 led to the adduct containing both OH and NH 2 groups (Scheme 45). 97 The empirical formula calculated from the results of elemental analysis is C 60 (OH) 8.7 -(NH 2 ) 3.5 H 3.5 Á3HCl.…”

Section: Oxygenation Of C 60mentioning

confidence: 99%

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Mechanochemistry of fullerenes and related materials

2013

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The low or lack of solubility of fullerenes, carbon nanotubes and graphene/graphite in organic solvents and water severely hampers the study of their chemical functionalizations and practical applications. Covalent and noncovalent functionalizations of fullerenes and related materials via mechanochemistry seem appealing to tackle these problems. In this review article, we provide a comprehensive coverage on the mechanochemical reactions of fullerenes, carbon nanotubes and graphite, including dimerizations and trimerizations, nucleophilic additions, 1,3-dipolar cycloadditions, Diels-Alder reactions, [2 + 1] cycloadditions of carbenes and nitrenes, radical additions, oxidations, etc. It is intriguing to find that some reactions of fullerenes can only proceed under solvent-free conditions or undergo different reaction pathways from those of the liquid-phase counterparts to generate completely different products. We also present the application of the mechanical milling technique to complex formation, nanocomposite formation and enhanced hydrogen storage of carbon-related materials.

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“…Adduct FOL synthesised in two variants was chosen as the water-soluble nanocarbon compound: FOL-1the product of the mechanochemical hydroxylation of a C 60 /C 70 mixture; FOL-2 -polyhydroxylated fullerene of composition C 60 (OH) 28 [13]. For the manufacture of specimens, one layer of finished reinforcing glass fabric was placed between two layers of the untreated film (the film technology method [14]) with heating to 220-235°C in a melt under a pressure of 2.5 MPa.…”

Section: Methodsmentioning

confidence: 99%

Investigating the Effect of Polymeric Finishing Agents on the Physicomechanical Properties of Glass-Fibre-Reinforced Plastics Based on Thermoplastic Matrices

Shershneva

Lesnichaya

Muradyan

et al. 2014

International Polymer Science and Technology

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An investigation was made of the modifying effect of finishing additives of polyvinyl alcohol and SKN-8 nitrile butadiene rubber on the elastic strength and dissipative relaxation properties of single-layer glassfibre-reinforced plastics based on polyethylene and polyamine matrices. It was shown that these modifying additives promote a reduction in residual internal stresses at the phase boundary, greater adhesion interaction between the surface of the reinforcing glass fibres and the thermoplastic polymer matrix, and accordingly strengthening of the polymer composites, especially in the case of a polyethylene matrix.

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Mechanochemical synthesis and properties of fullerene derivatives

Cited by 4 publications

References 3 publications

Eco‐Friendly and Scalable Synthesis of Fullerenols with High Free Radical Scavenging Ability for Skin Radioprotection

Eco‐Friendly and Scalable Synthesis of Fullerenols with High Free Radical Scavenging Ability for Skin Radioprotection

Mechanochemistry of fullerenes and related materials

Investigating the Effect of Polymeric Finishing Agents on the Physicomechanical Properties of Glass-Fibre-Reinforced Plastics Based on Thermoplastic Matrices

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