Median Raphe Cyst With Ciliated Cells: Report of a Case

Ciliated Median Raphe Cyst of Perineum Presenting as Perianal Polyp: A Case Report with Immunohistochemical Study, Review of Literature, and Pathogenesis

“…The presence of squamous cells in the cyst wall along with columnar epithelium in the presented case favors the metaplastic origin of ciliated cells. The other exceptional feature of this case is that it is reported as the first case of median raphe cyst of the perineum having ciliated cells in the cyst wall (the previously two reported cases being present on the penis) [11,12] in the English literature. Fortunately, benign behavior of these cysts permits curative excision, although recurrences have been documented [2].…”

“…The distinctive feature of this case is presence of ciliated cells in epithelium, which represents the third such case in the English literature. This case also represents the eldest of such patients; the previously reported cases of ciliated median raphe cyst being 24 and 30 years old [11,12]. Ciliated epithelium is present in the specific locations such as respiratory tract, middle ear, uterus and oviducts, ependymal epithelium of central nervous system, and ductuli efferentes testis.…”

Median Raphe Cyst with Ciliated Cells of the Penis

“…Ciliated epithelial cells are present in the respiratory tract, middle ear, uterus and oviducts, ependymal epithelium ofthe central nervous system and ductulus efTerens ofthe testis in human adults (5). secondary to irritation or local stimulation (2,5). They have been given various names, such as bronchogenie cysts, vulvar cysts and cutaneous ciliated cysts according to their topographical location.…”

Dermal cysts: a dermatopathological perspective and histological reappraisal

“…The cysts are lined by pseudostratified columnar epithelium that becomes more stratified squamous in nature as the urethral meatus is approached. Ciliated cells are rare but do occur, 92 and mucus glands are commonly present in the wall. Cytokeratin 7 and 13 positivity, along with positivity for CAM 5.2 and CEA, suggests mucinous columnar epithelium undergoing immature urothelial metaplasia 91…”