Medical Genetics, Genomics and Bioinformatics Aid in Understanding Molecular Mechanisms of Human Diseases

Abstract

Molecular mechanisms of human disease progression often have complex genetic underpinnings, and sophisticated sequencing approaches coupled with advanced analytics [...]

Recent Trends in Cancer Genomics and Bioinformatics Tools Development

“…We overview recent research trends in cancer genomics, bioinformatics tools development and medical genetics, based on results discussed in papers collections "Medical Genetics, Genomics and Bioinformatics" (https://www.mdpi.com/journal/ijms/special_ issues/Medical_Genetics_2021). This Special Issue continues publications on the "Medical Genetics, Genomics and Bioinformatics" topic presented in International Journal of Molecular Sciences from 2019-2020 (https://www.mdpi.com/journal/ijms/special_issues/Medical_ Genetics_Bioinformatics) and 2020-2021 (https://www.mdpi.com/journal/ijms/special_ issues/Medical_Genetics_Bioinformatics_2), based on the series of medical research conferences held in Russia [1,2].…”

“…This Special Issue on medical genomics shows that bioinformatics tools for the analysis of human diseases are in high demand [2,42]. The outputs of disease model analysis come in the form of sets of genes and protein markers which represent a particular interest to medical practitioners [1,2].…”

“…This Special Issue on medical genomics shows that bioinformatics tools for the analysis of human diseases are in high demand [2,42]. The outputs of disease model analysis come in the form of sets of genes and protein markers which represent a particular interest to medical practitioners [1,2]. "Medical Genetics, Genomics and Bioinformatics" journal issues will be continued in association with BGRS-2022 conference and related symposia (https://bgrssb.icgbio.ru/2022/).…”

Editorial: Bioinformatics of Genome Regulation, Volume II

“…Starting in 2018, materials of the conference materials in genetics and genomics were presented in Frontiers in Genetics , and due to popular demand in 2021 it was extended as the Volume II. The BGRS conference series have been presented at special journal issues earlier ( Orlov et al, 2016 ; Tatarinova et al, 2019 ; Orlov et al, 2015 ; Orlov et al, 2019a ; Orlov et al, 2019b ; Baranova et al, 2019 ) and recently ( Tatarinova et al, 2020 ; Orlov and Baranova, 2020 ; Orlov et al, 2020 ; Orlov et al, 2021a ; Orlov et al, 2021b ). We have to acknowledge “Bioinformatics of Gene Regulations and Structure” special issue at MDPI IJMS ( https://www.mdpi.com/journal/ijms/special_issues/Bioinformatics_Genomics ), as well as PeerJ journal BGRS-2020 collection ( https://peerj.com/collections/72-bgrs-sb-2020 ).…”

Bioinformatics Applications to Reveal Molecular Mechanisms of Gene Expression Regulation in Model Organisms

“…The current Special Issue contains eight research manuscripts and one review, each concerning a model or a pipeline applied to extract information useful for understanding the molecular mechanisms of gene expression regulation. We continue the previously published set of paper collections with an overarching theme of bioinformatics initially focused only on biomedical applications ( ) [ 2 , 3 ]. This Special Issue is focused on the deciphering of the molecular mechanisms underpinning chronic diseases and disorders.…”