Médicaments majorant le risque de chute : étude prospective au CHRU de Strasbourg

Minary, A.; Lambert-Kuhn, E.; Gourieux, B.; Bonnomet, F.; Vogel, Thomas; Lang, Pierre-Olivier

doi:10.1016/j.npg.2015.12.002

Cited by 2 publications

(9 citation statements)

References 43 publications

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“…The majority of falls occurred at home (64%) in our study as in other studies [4,21]. These figures could be justified by the fact that the senior spend most of their time at home.…”

Section: Falls Locationssupporting

confidence: 82%

“…These puddles may have been caused by inadvertent liquid substances (water, coffee, tea, juice...) or splashing due to the strong jets of the faucets. Pin [21] found the same extrinsic factors in his study, tripping and slipping (95%).…”

Section: Risk Factors For Fallssupporting

confidence: 57%

“…Among seniors who had a decrease in visual acuity 77% had fallen once. This prevalence of falls is much greater than the results of studies of Pin [20] and Minary [21].…”

Section: Visual Disordersmentioning

confidence: 55%

“…Contusion of superficial soft tissue was the major mechanical complication (62%); however, lower frequencies were found only in the Pradnya D [11] (25%) and Pin [20] studies (44%). Superficial injuries accounted for 15% of fallers, a frequency identical to that of Grundstorm [13] (14%) but below the results of Hdiji [12] (25%) and Pin [21] (18%). The fractures concerned only 15% of the fallers.…”

Section: The Complications Related To Fallsmentioning

confidence: 75%

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The Determinants of Fall in the Elderly at the Geriatric Center of Ouakam (Senegal)

Kâ¹,

Ghébi²,

Ndiaye³

et al. 2019

WJPH

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In Sénégal, the reality of falls in the elderly, despite their being a serious problem, are not well-known to the général public because the epidemiological data do not take them into account. This study aims at analyzing falls in elderly people who come for consultation at the gerontology and geriatrics center of Ouakam, focusing in particular on their frequency and their determinants. This was a descriptive cross-sectional study that was conducted from May 9 to July 10, 2016 at the Gerontology and Geriatrics Center. The population under investigation consisted of 210 patients with a female prédominance (61%), an average age of 69 years, 72% married, 22% practiced physical activity, 54% had a normal weight, 58% took more of a medicine. The most common pathologies were visual acuity (70%), arterial hypertension (52%), osteoarthritis (25%)... The most prescribed drug classes were hypotensives (33%), analgesics (13%), antidiabetics drugs (10%). The frequency of the falls in our population was 27% and they usually occurred at home (65%). The determinants of the falls were soil barriers (35%), loss of balance (22%), wet surfaces (16%), stairs (8%)... The number of medications taken per patient was only one factor statistically correlated with the number of falls. Bruising accounted for most of the mechanical complications (62%) but all patients had developed a phobia for falling again. Recommendations have been made for better management of these falls.

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“…The majority of falls occurred at home (64%) in our study as in other studies [4,21]. These figures could be justified by the fact that the senior spend most of their time at home.…”

Section: Falls Locationssupporting

confidence: 82%

Section: Risk Factors For Fallssupporting

confidence: 57%

“…Among seniors who had a decrease in visual acuity 77% had fallen once. This prevalence of falls is much greater than the results of studies of Pin [20] and Minary [21].…”

Section: Visual Disordersmentioning

confidence: 55%

Section: The Complications Related To Fallsmentioning

confidence: 75%

See 2 more Smart Citations

The Determinants of Fall in the Elderly at the Geriatric Center of Ouakam (Senegal)

Kâ¹,

Ghébi²,

Ndiaye³

et al. 2019

WJPH

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“…A total of 31 studies (32 articles) published between 2008 and 2023 met the inclusion criteria (Figure 1). Sample size varied from 50 26 to 2,997,872 27 individuals (Table 1). Hip fractures was the most studied outcome (n = 16 (17 articles) 26,[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43] ), followed by all bone fractures (n = 12 27,[44][45][46][47][48][49][50][51][52][53][54] ), upper limb fractures (n = 2 55,56 ), and fragility fractures (n = 1 57 ).…”

Section: Study Selection and Characteristicsmentioning

confidence: 99%

Polypharmacy and risk of fractures in older adults: A systematic review

Gagnon,

Talbot,

Tremblay

et al. 2024

J Evidence Based Medicine

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BackgroundFractures have serious health consequences in older adults. While some medications are individually associated with increased risk of falls and fractures, it is not clear if this holds true for the use of many medications (polypharmacy). We aimed to identify what is known about the association between polypharmacy and the risk of fractures in adults aged ≥65 and to examine the methods used to study this association.MethodsWe conducted a systematic review with narrative synthesis of studies published up to October 2023 in PubMed, Embase, CINAHL, PsychINFO, Cochrane Library, Web of Science, and the grey literature. Two independent reviewers screened titles, abstracts, and full texts, then performed data extraction and quality assessment.ResultsAmong the 31 studies included, 11 different definitions of polypharmacy were used and were based on three medication counting methods (concurrent use 15/31, cumulative use over a period 6/31, daily average 3/31, and indeterminate 7/31). Overall, polypharmacy was frequent and associated with higher fracture risk. A dose–response relationship between increasing number of medications and increased risk of fractures was observed. However, only seven studies adjusted for major confounders (age, sex, and chronic disease). The quality of the studies ranged from poor to high.ConclusionsPolypharmacy appears to be a relevant modifiable risk factor for fractures in older individuals that can easily be used to identify those at risk. The diversity of medication calculation methods and definitions of polypharmacy highlights the importance of a detailed methodology to understand and compare results.

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Médicaments majorant le risque de chute : étude prospective au CHRU de Strasbourg

Cited by 2 publications

References 43 publications

The Determinants of Fall in the Elderly at the Geriatric Center of Ouakam (Senegal)

The Determinants of Fall in the Elderly at the Geriatric Center of Ouakam (Senegal)

Polypharmacy and risk of fractures in older adults: A systematic review

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