Medication Adherence in Children

Alsous, Mervat

doi:10.4172/2472-1654.100048

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…10 Notwithstanding this, full adherence to chronic medications is rare, especially in pediatric settings. 15,19 In our experience, only 7 of 17 patients (41%) showed adherence to therapy during all of the follow-up time (Fig. 2).…”

Section: Discussionmentioning

confidence: 74%

Impact of Adherence (Compliance) to Oral Acyclovir Prophylaxis in the Recurrence of Herpetic Keratitis: Long-Term Results From a Pediatric Cohort

Luccarelli

Lucentini

Martellucci

et al. 2020

Cornea

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Purpose: To evaluate the long-term role of adherence to oral acyclovir prophylaxis in reducing the risk for recurrent herpes simplex virus keratitis (HSK) in children.Methods: A retrospective cohort study was performed including all pediatric patients 16 years or younger) with their first HSK diagnosis and treatment at our center. Children were started on a standardized oral acyclovir prophylactic regimen after the acute phase. Adherence to prophylaxis was assessed monthly through parent interviews. The possible association between any recurrence (not only the first) and exposure to acyclovir prophylaxis was evaluated using random-effects multivariate logistic regression.Results: A total of 20 eyes of 17 patients (8 boys and 9 girls) were included. The mean follow-up time was 3.5 years. Adherence to acyclovir prophylaxis was registered in 100% of patients with no recurrences and in 36.4% of patients with 1 or more recurrences (P = 0.035). All other tested variables (time of follow-up, sex, age, infectious diseases, underlying hematological diseases, eye, and HSK type) did not differ between the 2 groups. The multivariate model confirmed the lower risk for recurrence in patients who were compliant to therapy (adjusted odds ratio 0.04, 95% confidence intervals 0.00-0.42, P = 0.008). No adverse effects were recorded during follow-up.Conclusions: Oral acyclovir prophylaxis is a safe and an effective medical treatment for recurrent HSK and its long-term efficacy is associated with compliance to the therapy.

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Section: Discussionmentioning

confidence: 74%

Impact of Adherence (Compliance) to Oral Acyclovir Prophylaxis in the Recurrence of Herpetic Keratitis: Long-Term Results From a Pediatric Cohort

Luccarelli

Lucentini

Martellucci

et al. 2020

Cornea

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“…None of these measurement techniques quantify exactly what each patient has taken and should be considered as measuring variables that are indicative of adherence rather than being measures of absolute medication use [104]. They do, however, provide an opportunity to triangulate multiple effective methods to provide accurate assessments of adherence [68,97].…”

mentioning

confidence: 99%

Overview of Self-Management Skills and Associated Assessment Tools for Children with Inflammatory Bowel Disease

Vernon‐Roberts

Gearry

Day

2021

Gastrointestinal Disorders

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Self-management is a multi-modal approach for managing chronic conditions that encompasses a number of different elements; knowledge, adherence, self-regulation, communication, and cognitive factors. Self-management has been shown to be beneficial for adults with inflammatory bowel disease (IBD), and for children with IBD it may help them learn to take control of their complex treatment regimens and lead to positive disease outcomes. The development of self-management skills for children with IBD is vital in order to maximize their potential for health autonomy, but it is still an emergent field in this population. This review provides an over-arching view of the self-management elements specific to children with IBD, and highlights outcome measures that may be used to assess skills within each field as well as the efficacy of targeted interventions.

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“…The threshold for non-adherence can differ depending on the patient, drug and disease; however, it is significant when it changes the desired therapeutic effect (Alsous, 2017). In most studies, there is no standard operational definition of adherence (Becker & Maiman, 1975;DiMatteo, 2004) since the division between adherence and non-adherence is not consistent (Matsui, 2007).…”

Section: What Is Medication Adherence?mentioning

confidence: 99%

“…Adherence to treatment regimens is crucial in successful treatment (Osterberg & Blaschke, 2005;Becker et al, 1972) and poor medication adherence may lead to serious consequences (DiMatteo, 2003). Non-adherence may directly affect treatment by negatively impacting the potential benefits of the medication (Becker & Maiman, 1975;Matsui, 2007;Dean et al, 2010;DiMatteo, 2003;Butz, 2006;Alsous, 2017), reducing the patients' quality of life (DiMatteo, 2004), and potentially leading to suffering (DiMatteo, 2004) or higher mortality rates (DiMatteo, 2004). This could lead to frustration, anger or hopelessness for both the healthcare provider and the patient (DiMatteo, 2004).…”

Section: Why Medication Non-adherence Is An Issuementioning

confidence: 99%

Improving Adherence to Ongoing Treatments in Young Adults Through Design

Hafezi¹

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Medication non-adherence is a major issue and young adults have unique circumstances leading to non-adherence. User-centered design methods and a constructivist approach were used to address this issue through exploratory, qualitative research. An initial review of the literature framed the project scope and identified knowledge on the issues/interventions for medication adherence. Interviews were conducted with individuals in the target demographic to identify their current approach and issues with medication adherence. Information collected informed co-design sessions, which gathered information on users needs and desires to improve adherence. Results from the literature review, interview and co-design sessions were analysed to create design considerations for a tool that assists in medication taking for the target demographic.These considerations include functional, experiential and healthcare system guidelines.Findings of this study are an initial step towards developing a solution to this issue and the methods used can be applied to future research.

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Medication Adherence in Children

Cited by 4 publications

References 8 publications

Impact of Adherence (Compliance) to Oral Acyclovir Prophylaxis in the Recurrence of Herpetic Keratitis: Long-Term Results From a Pediatric Cohort

Impact of Adherence (Compliance) to Oral Acyclovir Prophylaxis in the Recurrence of Herpetic Keratitis: Long-Term Results From a Pediatric Cohort

Overview of Self-Management Skills and Associated Assessment Tools for Children with Inflammatory Bowel Disease

Improving Adherence to Ongoing Treatments in Young Adults Through Design

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