Medication Adherence in Patients With Uncontrolled Hypertension &amp; Hypertensive Crisis Presenting to a Hospital Setting in Karachi, Pakistan

Yousuf, Fatimah S; Khan, Muhammad Arbaz A; Bibi, Raheela; Arif, Aiman; Arshad, Ayesha; Almas, Aysha

doi:10.7759/cureus.33995

Cited by 4 publications

(6 citation statements)

References 28 publications

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“…The combined effect of hemodynamic factors has the most negative impact on arterial branches, which in most cases causes the formation of aneurysms at the bifurcations of cerebral vessels (Gao et al, 2022). The causes of aneurysms are high BP, atherosclerosis, acquired traumas, heredity and abnormal blood flow at the junction where the arteries meet (Wedro, 2022;Veeturi et al, 2021).…”

Section: Review and Discussion 1 Etiology Pathogenesis Risk Factors F...mentioning

confidence: 99%

The value of diagnostic procedures for essential hypertension control after an early recovery period of hemorrhagic stroke (literature review)

Tkachyshyn,

Bespalova

2024

USMYJ

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hemorrhagic stroke is the most severe type of stroke, which is more likely to lead to death and severe disability. Although there are many causes and risk factors for hemorrhagic stroke – both congenital and acquired, and mostly their combination – essential hypertension is the most common and leading cause of intracranial hemorrhage. This study aimed to make a comprehensive overview on the value of diagnostic procedures for essential hypertension control after an early recovery period of hemorrhagic stroke. The analyzed data were observed on PubMed and Ukrainian scientific sources concerning essential hypertension course in post-hemorrhagic stroke patients in relation to further prophylaxis in stable phase. All the observed manuscripts were published within the period 2014-2024. The focus of attention was made predominantly on the essential hypertension as the key factor for hemorrhagic stroke development. From the literature review, it could be concluded that the problem of essential hypertension control after hemorrhagic stroke is relevant today and needs a thorough solution to prevent the re-occurrence of cerebrovascular events. For a rational approach to the management of hypertensive patients with hemorrhagic stroke medical history, it would be necessary to perform a set of diagnostic procedures, which would include ultrasound examination of the major cervical arteries, echocardiography, 24-hour ambulatory blood pressure and electrocardiogram monitoring, determination of plasma cholesterol panel indices and blood coagulation tests.

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Section: Review and Discussion 1 Etiology Pathogenesis Risk Factors F...mentioning

confidence: 99%

The value of diagnostic procedures for essential hypertension control after an early recovery period of hemorrhagic stroke (literature review)

Tkachyshyn,

Bespalova

2024

USMYJ

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“…В литературе значительное внимание уделяется форме приёма АГТ [9]. В настоящее время при лечении АГ отдаётся предпочтение назначению АГП в виде фиксированной комбинации [12]. В то же время, анализ данных, полученных в нашем исследовании, показал невысокую распространённость назначения фиксированных комбинаций пациентам группы 1 -21,5%.…”

Section: Original Article Antihypertensive Therapy and Medication Adh...unclassified

“…По результатам нашего исследования доля приверженных к назначаемой АГТ пациентов с более частыми подъёмами уровня АД составляет 38,3%. Аналогичные результаты были получены Yousuf F. и соавт., в котором распространённость пациентов с кризовым повышением АД, выполняющих рекомендации врача, составила 40,7% [12].…”

Section: Original Article Antihypertensive Therapy and Medication Adh...unclassified

Antihypertensive therapy and medication adherence in patients with uncontrolled arterial hypertension

Solntseva,

Sivakova,

Aksenova

et al. 2023

Evrazijskij kardiologičeskij žurnal

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Aim. To evaluate the antihypertensive therapy and adherence to treatment in patients with uncontrolled arterial hypertension.Materials and Мethods. The study included 297 patients hospitalized at the E.I. Chazov National Medical Research Center of Cardiology over the period from September 2019 to March 2022. Patients were spread into two groups depending on the increase in the frequency of BP: group 1 (n=149) – increase in BP above 140/90 mm Hg 1 or more per week while taking antihypertensive therapy with clinical manifestations, and group 2 (n=148) – increase in blood pressure more than 140/90 mm Hg less than 1 per week while taking antihypertensive therapy clinical manifestations. Antihypertensive therapy and medication adherence were assessed at hospital discharge and after 12 months.Results. Initially, the number of antihypertensive drugs was greater in patients with group 1 versus the patients with group 2 (p<0,001). The frequency of taking antihypertensive therapy initially and after 12 months was greater in group 1 (p<0,001). After 12 months, the number of antihypertensive drugs decreased in the group 1, and remained the same in group 2. When comparing the different classes of antihypertensive drugs, all classes, except angiotensin-converting enzyme inhibitors were most frequently prescribed in group 1 (p<0,05). After 12 months, a lower level of adherence was observed in group 1 patients compared to group 2 (6 [5-8] points vs. 8 [6-9] points) (p<0,001), as evidenced in the reduced intake of different classes of antihypertensive therapy.Conclusion. Uncontrolled arterial hypertension is a release of hypertension associated with more antihypertensive medications to be prescribed and adherence to be monitored more closely.

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“…For instance, a study reported that 37.7% of patients who visited a clinic setting in Islamabad were non-adherent to their antihypertensive medications (Mahmood et al, 2020). Similarly, in another study, 36% of inpatients who attended a healthcare setting in Karachi were observed to be non-adherent (Yousuf et al, 2023). In another study, it was observed that a large proportion of patients with rheumatoid arthritis were adherent to their therapy (Naqvi et al, 2020a).…”

Section: Introductionmentioning

confidence: 99%

“…Adherence to long-term medications for chronic illness is a global issue. Adherence to medication can be explained as the extent to which a patients’ dietary and medicine taking behavior, and lifestyle is consistent to the recommended instructions from a healthcare provider ( Yousuf et al, 2023 ; World Health Organization WHO, 2003 ). Non-adherence to medication not only has clinical implications but is one of the core reasons for additional health expenditure owing to complications and hospital admissions.…”

Section: Introductionmentioning

confidence: 99%

Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases

Islam,

Iffat,

Imam

et al. 2023

Front. Pharmacol.

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Background: There is no medication adherence scale available in Sindhi language currently. Hence, the Sindhi speaking population will either use a translator or provide their medical history in another language for documentation of medical conditions. This poses a challenge in monitoring and evaluating adherence to medications within this linguistic community.Aim: The aim of this study was to translate and validate the Sindhi version of the General Medication Adherence Scale (GMAS-S) in patients with chronic diseases.Methods: This was a cross-sectional study of 4 months duration and was conducted in out-patient department of a university affiliated hospital in Karachi, Pakistan. All adults with chronic diseases, who were on long-term medications, and able to read and understand Sindhi language were invited. Convenience sampling was employed and a questionnaire consisting of demographic questions and the Sindhi version of GMAS was used. The translation of the scale was carried out. Confirmatory factor analysis (CFA) was conducted, and a structural equation model (SEM) was developed. Fit indices, namely, goodness of fit index (GFI), adjusted goodness of fit index (AGFI), Tucker Lewis index (TLI), comparative fit index (CFI), and root mean square error of approximation (RMSEA) were reported. Reliability was assessed using Cronbach’s alpha (α), intraclass correlation coefficient (ICC), corrected item-to-total correlation (ITC) and item deletion. Data were analysed through IBM SPSS version 23 and IBM AMOS version 25. The study obtained ethical clearance.Results: A total of 150 responses were analysed. The reliability of the Sindhi version of GMAS was (α) = 0.696. The intraclass correlation coefficient (ICC) was reported at 0.696 (95% CI: 0.618–0.763). The values for the fit indices were as follows: χ2/df = 1.84, GFI = 0.918, TLI = 0.920, CFI = 0.942, AGFI = 0.864, and RMSEA = 0.075. All values except AGFI were in the acceptable ranges and indicated good fitness. Most participants (80.7%) appeared non-adherent to their medications.Conclusion: The results of the study demonstrate that the Sindhi version of the GMAS is a valid and reliable scale to measure adherence in Sindhi speaking persons with chronic diseases.

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Medication Adherence in Patients With Uncontrolled Hypertension & Hypertensive Crisis Presenting to a Hospital Setting in Karachi, Pakistan

Cited by 4 publications

References 28 publications

The value of diagnostic procedures for essential hypertension control after an early recovery period of hemorrhagic stroke (literature review)

The value of diagnostic procedures for essential hypertension control after an early recovery period of hemorrhagic stroke (literature review)

Antihypertensive therapy and medication adherence in patients with uncontrolled arterial hypertension

Translation and validation of the Sindhi version of the general medication adherence scale in patients with chronic diseases

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