Medication Prediction with Electroencephalography Phenotypes and Biomarkers

Gunkelman, Jay

doi:10.5298/1081-5937-42.2.03

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…ADHD is associated with an excess of theta and, in some cases, low alpha, that is, an excess of subcortical processing. The theta/beta ratio has FDA approval as a diagnostic marker in ADHD [52]. A consistent decrease in beta power measured at the brain stimulation site was correlated with a significant and sustained reduction in depressive symptoms [53].…”

Section: Discussionmentioning

confidence: 97%

Brain Waves Reflect Cognition-Emotion State as a Diagnostic Tool for Intervention in Dysfunctional States: A Real-World Evidence

Mayoral-Rodrígez

Pérez-Alvarez

Timoneda-Gallart

2022

J. Intellect. Disabl. Diagn. Treat.

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Objective: This study aims to characterize electrical signals to establish a diagnosis of cognitive-emotional dysfunction and guide a successful therapeutic intervention. Therefore, the present study aimed to observe these frequency bands in a sample of dysfunctional neurological behaviors to establish a neural marker of neural dysfunction that helps diagnose and monitor treatment. Methods: A descriptive retrospective (extracted from the database) observational study design based on real-world historical data from routine clinical practice. According to DSM-5, low academic achievement (n =70), disruptive behavior (externalizing behavior problems) (n=70), and somatic syndrome disorder (n=70) were the subjects. The mean age of the sample was 14.13 (SD = 1.46; range 12-18), 31.5% women. The measuring instrument was the NeXus-10, which is suitable for acquiring a wide range of physiological signals. Brain electrical activity was recorded by using the quantitative electroencephalograph (qEEG) in accordance with the 10-20 International Electrode Placement System. In particular, the specific form of miniQ (mini-qEEG) was used. Results: A pattern record present in all cases were identified. The record refers to (a) activity along the midline, namely, Fz-Cz-Pz, (b) activity from the center (Cz) to back, namely, Pz-O1 and O2, (c) activity from the center (Cz) forward (Fz), and (d) comparison between hemispheres. The characteristics of theta, alpha, and beta waves define the characteristic pattern of neurological dysfunction. The reversal of the dysfunctional pattern coincided with the remission of the clinical symptoms after treatment, which occurred in 87,6% of the subjects. We define remission as not meeting DSM-5 criteria. Conclusion: This study suggests that miniQ register could be considered a simple and objective tool for studying neurological dysfunction. This dysfunction is explained according to current neurological knowledge of interactive cognition-emotion processing. MiniQ may be a cheap and reliable method and a promising tool for the investigation in the field.

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Section: Discussionmentioning

confidence: 97%

Brain Waves Reflect Cognition-Emotion State as a Diagnostic Tool for Intervention in Dysfunctional States: A Real-World Evidence

Mayoral-Rodrígez

Pérez-Alvarez

Timoneda-Gallart

2022

J. Intellect. Disabl. Diagn. Treat.

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“…A practitioner must know how to choose the correct tool for each kind of analysis. "You are only as good as your data and your ability to quantitatively process that data" (Gunkelman, 2014). For example, the "correct" montage is the one that allows you to verify the signal source in a particular way.…”

Section: Mastering Eeg Toolsmentioning

confidence: 99%

The Suisun Summit 2022: Emerging Themes and Open Questions in qEEG and Neurotherapies

West¹,

Tracy²,

Swatzyna³

et al. 2023

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The Suisun Summit 2022 was a gathering of 70 clinicians, educators, and researchers in quantitative electroencephalography and neurofeedback. During this 5-day event, several themes emerged in talks or discussion groups: EEG/qEEG Reading Skills; Medication Effects and Pharmaco-EEG; Technological Advancements; Emerging Concerns; and Growing Community Prestige through Research. Participants were asked to summarize what they believed to be the most important messages from the event to share with colleagues who were not in attendance, resulting in this review. A unifying concept for all the themes was a desire for higher quality, standardized EEG/qEEG education that provides depth as well as breadth. Models of clinical care that encourage open communication with prescribers and functional medicine specialists were strongly emphasized. Abstracts from all presentations are attached in Addendum B.

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Treat the Condition Not the Label

Swingle

2015

Adding Neurotherapy to Your Practice

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Medication Prediction with Electroencephalography Phenotypes and Biomarkers

Cited by 5 publications

References 19 publications

Brain Waves Reflect Cognition-Emotion State as a Diagnostic Tool for Intervention in Dysfunctional States: A Real-World Evidence

Brain Waves Reflect Cognition-Emotion State as a Diagnostic Tool for Intervention in Dysfunctional States: A Real-World Evidence

The Suisun Summit 2022: Emerging Themes and Open Questions in qEEG and Neurotherapies

Treat the Condition Not the Label

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