Mediterranean Diet as a Tool to Combat Inflammation and Chronic Diseases. An Overview

Tsigalou, Christina; Konstantinidis, Theocharis; Paraschaki, Afroditi; Stavropoulou, Elisavet; Voidarou, C.; Bezirtzoglou, Eugenia

doi:10.3390/biomedicines8070201

Cited by 117 publications

(94 citation statements)

References 106 publications

(122 reference statements)

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“…The Mediterranean diet is associated with a high intake of extra-virgin olive oil, fruits, vegetables, nuts, cereals and legumes, moderate intakes of fish, and low intakes of red meat, sweets and eggs [ 102 ]. This diet is rich in polyphenols, lycopene, trace elements, minerals, vitamins and omega-3 fatty acids [ 103 ]. Studies conclude that the Mediterranean diet, known as a “long life” diet, even when it is adapted to other countries’ eating habits, has a key role in health promotion and CD prevention [ 104 , 105 ].…”

Section: Link Between Nutrition Periodontitis and Other Main Chromentioning

confidence: 99%

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Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases

Martinon

Fraticelli

Giboreau

et al. 2021

JCM

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Nutrition is recognized as an essential component in the prevention of a number of chronic diseases, including periodontal disease. Based on these considerations, a better understanding is required regarding how the diet, and more particularly the intake of macronutrients and micronutrients, could impact the potential relationship between nutrition and periodontal diseases, periodontal diseases and chronic diseases, nutrition and chronic diseases. To overcome this complexity, an up-to-date literature review on the nutriments related to periodontal and chronic diseases was performed. High-sugar, high-saturated fat, low-polyols, low-fiber and low-polyunsaturated-fat intake causes an increased risk of periodontal diseases. This pattern of nutrients is classically found in the Western diet, which is considered as an ‘unhealthy’ diet that causes cardiovascular diseases, diabetes and cancers. Conversely, low-sugar, high-fiber and high-omega-6-to-omega-3 fatty acid ratio intake reduces the risk of periodontal diseases. The Mediterranean, DASH, vegetarian and Okinawa diets that correspond to these nutritional intakes are considered as ‘healthy’ diets, reducing this risk of cardiovascular diseases, diabetes and cancers. The role of micronutrients, such as vitamin D, E, K and magnesium, remains unclear, while others, such as vitamin A, B, C, calcium, zinc and polyphenols have been shown to prevent PDs. Some evidence suggests that probiotics and prebiotics could promote periodontal health. Periodontal and chronic diseases share, with a time delay, nutrition as a risk factor. Thus, any change in periodontal health should be considered as a warning signal to control the dietary quality of patients and thus reduce the risk of developing chronic diseases later on.

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Section: Link Between Nutrition Periodontitis and Other Main Chromentioning

confidence: 99%

“…The preventive action of the diet is probably due to the anti-inflammatory and antioxidative properties of its components. The diet is thought to act by improving autophagy, Th cells imbalance, cell adhesion, complement activity and oxidative stress [ 103 ].…”

Section: Link Between Nutrition Periodontitis and Other Main Chromentioning

confidence: 99%

Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases

Martinon

Fraticelli

Giboreau

et al. 2021

JCM

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“…All this has resulted in the decrease in patients diagnosed with OME and it begins to be a rare disease in children of our pediatric quota who follow TMD [23]. The growing interest in the Mediterranean diet is based on its role in inflammatory diseases [24]. Several clinical and epidemiological studies, as well as experimental studies show that the consumption of the DMT reduces the the immune system such as cancer, atherosclerosis or cardiovascular disease [25].…”

Section: Resultsmentioning

confidence: 99%

Effects of the Traditional Mediterranean Diet in Patients with Otitis Media with Effusion

Calatayud-Sáez¹,

Calatayud²,

Calatayud³

2021

Preprint

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Introduction: Otitis media with effusion (OME) is common in pediatric primary care consultations. Its etiology is multifactorial, although it has been proven that inflammation factors mediate and that immunity is in a phase of relative immaturity. The objective of this study was to assess the effects of the Traditional Mediterranean Diet (TMD) modulating inflammation and immunity in patients diagnosed with OME.

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“…Many studies have examined the influence of specific eating patterns to the gut microbiome [ 106 , 107 , 108 ]. Animal studies stated that several Lactobacillus and Bifidobacterium species could prevent or even impede the severity of T2DM [ 109 ].…”

Section: Functional Foods and Diabetesmentioning

confidence: 99%

Maintaining Digestive Health in Diabetes: The Role of the Gut Microbiome and the Challenge of Functional Foods

et al. 2021

Self Cite

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Over the last decades, the incidence of diabetes has increased in developed countries and beyond the genetic impact, environmental factors, which can trigger the activation of the gut immune system, seem to affect the induction of the disease process. Since the composition of the gut microbiome might disturb the normal interaction with the immune system and contribute to altered immune responses, the restoration of normal microbiota composition constitutes a new target for the prevention and treatment of diabetes. Thus, the interaction of gut microbiome and diabetes, focusing on mechanisms connecting gut microbiota with the occurrence of the disorder, is discussed in the present review. Finally, the challenge of functional food diet on maintaining intestinal health and microbial flora diversity and functionality, as a potential tool for the onset inhibition and management of the disease, is highlighted by reporting key animal studies and clinical trials. Early onset of the disease in the oral cavity is an important factor for the incorporation of a functional food diet in daily routine.

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Mediterranean Diet as a Tool to Combat Inflammation and Chronic Diseases. An Overview

Cited by 117 publications

References 106 publications

Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases

Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases

Effects of the Traditional Mediterranean Diet in Patients with Otitis Media with Effusion

Maintaining Digestive Health in Diabetes: The Role of the Gut Microbiome and the Challenge of Functional Foods

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