Meeting the challenges of acne treatment in Asian Patients: A review of the role of dermocosmetics as adjunctive therapy

Goh, Chee Leok; Noppakun, Nopadon; Micali, Giuseppe; Azizan, Noor Zalmy; Boonchai, Waranya; Chan, Yung; Cheong, Wai Kwong; Chiu, Pin Chi; Etnawati, Kristiana; Gulmatico-Flores, Zharlah; Foong, Henry; Kubba, Raj; Paz-Lao, Purita; Lee, Yin Yin; Loo, Steven King Fan; Modi, Farida; Nguyen, Trong Hao; Pham, Thi Lan; Shih, Yang Hsin; Sitohang, Irma Bernadette S.; Wong, Su Ni

doi:10.4103/0974-2077.184043

Cited by 32 publications

(63 citation statements)

References 61 publications

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“…Hydrating and emollient products should be noncomedogenic, hypoallergenic, non-irritating, and non-greasy, with an aqueous base. 76 It is highly important to use specific moisturizers that contain active ingredients of a sufficient quality and concentration to protect and repair the skin. Products with hyaluronic acid, glycerin, biosaccharides, oligosaccharides, or similar, are suitable.…”

Section: Our Experience and Recommendationsmentioning

confidence: 99%

<p>Challenges and Solutions in Oral Isotretinoin in Acne: Reflections on 35 Years of Experience</p>

Bettoli¹,

Guerra‐Tapia²,

Herane³

et al. 2019

CCID

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Acne vulgaris affects more than 80% of adolescents and young adults and forms a substantial proportion of the dermatologist's and general practitioner's caseload. Severity of symptoms varies but may result in facial scarring and psychological repercussions. Oral isotretinoin is highly effective but can only be prescribed by specialists. Side effects are recognized and mostly predictable, ranging from cosmetic effects to teratogenicity. These can affect patients' quality of life and treatment adherence. This article provides a commentary on 4 key areas: the use of oral isotretinoin vs oral antibiotics, including the importance of early recognition of nonresponse to treatment, the psychological effects of acne and isotretinoin treatment, the side effects of isotretinoin therapy, and cosmetic treatment options that can help alleviate predictable side effects. The authors, who have all participated in various international expert groups, draw on relevant literature and their extensive professional experience with oral isotretinoin in the treatment of acne. The aim of this article is to provide an informative and practical approach to managing oral isotretinoin treatment in patients with acne, to help optimize treatment of this skin disease.

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Section: Our Experience and Recommendationsmentioning

confidence: 99%

<p>Challenges and Solutions in Oral Isotretinoin in Acne: Reflections on 35 Years of Experience</p>

Bettoli¹,

Guerra‐Tapia²,

Herane³

et al. 2019

CCID

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“…It has been reported by some authors that people with pigmented skin often develop severe acne [3] [7] [8]. The majority of our patient had moderate (43.5%) and severe (34.7%) acne, compared with South Africa and French, where mild to moderate acne predominated [2] [16]. There is therefore an interracial but also intra-racial difference in the clinical presentation of acne.…”

Section: Discussionmentioning

confidence: 59%

Acne on Pigmented Skin: Epidemiological, Clinical and Therapeutic Features in Dermatology in Benin

Degboe¹,

Koudoukpo²,

Agbessi³

et al. 2019

JCDSA

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Purpose: The aim of this work was to describe the epidemiological, clinical and therapeutic features of pigmented skin acne in Benin. Methods: This was a prospective, cross-sectional and analytical study conducted in the dermatology departments of the Borgou-Alibori Departmental Teaching Hospital and the National Teaching Hospital Hubert Koutoukou Maga from January 2017 to December 2018, which has included black-skinned patients who were diagnosed with acne and gave their free and informed consent. The ECLA score was used for clinical evaluation of the severity of the acne. Results: We collected 129 patients including 35 men and 94 women. The median age of the patient was 24.6 years ± 8.5 years. The median age of onset was 17.9 years ± 7.6 years. The main triggering of worsening factors was inadequate self-medication (53.5%), excoriation (48.1%), certain foods (34.9%) and lightening cosmetic (32.5%). Most patients had inflammatory (51.9%) or comedonal (31.8%) acne associated with post-inflammatory hyperpigmentations (70.5%) and excoriated lesions (31%). In the majority of cases, acne was moderate in women (52.1%) and severe in men (62.8%) with p = 9 × 10 −3 . The lesions were electively seated in the face (95.3%), mainly on the forehead and cheeks. Active cosmetics (76.7%), retinoids (58.9%), oral antibiotics (55.8%), and benzoyl peroxide (48.9%) were the most commonly used therapeutic classes. Conclusion: The majority of young and adult women consulted for predominant inflammatory acne on the forehead and cheeks, moderate in woman and severe in men in Benin. The therapeutic arsenal consisted mainly of active cosmetics, retinoids, antibiotics and benzoyl peroxide.

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“…Multiple guidelines favor initial combination therapy with agents that affect different mechanisms of acne (Tuchayi et al, 2015;Vera, Patel, Cardwell, Saleem, & Feldman, 2017;Zaenglein et al, 2016). In most cases, topical acne treatment may be associated with some adverse skin irritation effects that can manifest as erythema, skin dryness, scaling, burning or stinging, and itching (Goh et al, 2016). Oral pharmacotherapies should be reserved for more severe acne that is unresponsive to topical pharmacotherapy to achieve faster, more complete acne resolution and combat antibiotic resistance (Bienenfeld, Nagler, & Orlow, 2017;Roman, Cifu, & Stein, 2016;Thomas, 2017;Tuchayi et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Retrospective Study: Initial Pharmacotherapy Profile of New Acne Vulgaris Patients

Wibisono

Indramaya

Rochmanti

2020

JBE

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Background: Acne Vulgaris (AV) is one of the most common diseases in the field of dermatology and ranks as the eighth most prevalent disease worldwide. Early management of this potentially deforming skin disease may reduce the pathophysiological burden and improve the quality of life of patients. Purpose: This study aimed to determine the pharmacotherapy for new patients with AV. Methods: This cross-sectional study used new patients with AV of the Cosmetic Division of the Outpatient Skin and Venereal Health Unit, Regional Public Hospital (RSUD) Dr. Soetomo, from January to December 2013 that were descriptively presented. The variable was the pharmacotherapy given. This study used secondary data collection by looking at the patients’ medical records. The variables studied were acne lesions and pharmacotherapy regimens, including the administration route and the medicine used. Results: The number of samples that met the inclusion criteria was 951 patients. Comedonal acne was most commonly given topical tretinoin. Papulopustular acne was most commonly given a topical combination of clindamycin and tretinoin, while acne conglobata was most commonly given a combination of topical clindamycin and tretinoin with oral doxycycline. Conclusion: The new patients with comedonal acne were mostly prescribed topical tretinoin pharmacotherapy. A pharmacotherapy combination of topical clindamycin and tretinoin was given to most new patients with papulopustular acne, whereas new patients with conglobata acne were given a pharmacotherapy combination of topical tretinoin and clindamycin with oral doxycycline.

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Meeting the challenges of acne treatment in Asian Patients: A review of the role of dermocosmetics as adjunctive therapy

Cited by 32 publications

References 61 publications

<p>Challenges and Solutions in Oral Isotretinoin in Acne: Reflections on 35 Years of Experience</p>

<p>Challenges and Solutions in Oral Isotretinoin in Acne: Reflections on 35 Years of Experience</p>

Acne on Pigmented Skin: Epidemiological, Clinical and Therapeutic Features in Dermatology in Benin

Retrospective Study: Initial Pharmacotherapy Profile of New Acne Vulgaris Patients

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