Megaduodenum associated with gastric strongyloidiasis

Silva, Amanda Pinter Carvalheiro da; Boteon, Yuri L.; Tercioti, Valdir; Lopes, Luiz Roberto; Neto, João de Souza Coelho; Andreollo, Nelson Adami

doi:10.1016/j.ijscr.2014.11.066

Cited by 5 publications

(7 citation statements)

References 9 publications

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“…However, it is theorized that neuropathic and myopathic disorders that lead to mproper duodenal motility may lead to functional megaduodenum [ 4 ]. These include congenital diseases (e.g., congenital ganglion cell deficiency, ganglion cell dysplasia, duodenal aganglionosis, hereditary megaduodenum, porphyria, abnormal distribution of cell of Cajal, and collagen diseases) and acquired diseases (e.g., diabetes mellitus, systemic lupus erythematosus, amyloidosis, scleroderma, polymyositis vitamin deficiency, Chagas disease, and post-vagotomy intestinal paralysis), which affect the function of the intestinal wall plexus or the smooth muscles [ 1 - 4 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…One of the clinical manifestations of megaduodenum associated malnutrition is pellagra, caused by vitamin B3 (niacin) deficiency [ 6 ]. Patients with megaduodenum may also experience abdominal distension, excessive salivation, hematemesis, recurrent acute appendicitis, steatorrhea, epigastric abdominal pain, dyspepsia, osteoporosis, gastric plenitude, and early satiety [ 4 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

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Idiopathic Megaduodenum in a Teenager: A Case Report

Eze,

Chime

et al. 2024

Cureus

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Megaduodenum is a rare clinical syndrome characterized by significant duodenal dilation, elongation, and hypertrophy. Given its rarity and nonspecific clinical manifestations, megaduodenum may be misdiagnosed, leading to delays in surgical care and increased morbidity. We describe a case of idiopathic megaduodenum in a teenage Caucasian female, who presented with a five-year history of halitosis, recurrent belching, bloating, nausea and vomiting, and postprandial epigastric abdominal pain. She was diagnosed with megaduodenum by dramatic findings on contrast radiography. She developed a duodenal volvulus necessitating emergency exploratory laparotomy, during which a duodenal plication and a side-to-side duodenojejunostomy were performed. Exploratory laparotomy and histopathological analysis were unrevealing of any definitive abnormalities to explain her megaduodenum. Postoperatively, she developed two early small bowel obstructions, both from subsequent adhesions requiring repeat laparotomy with adhesiolysis. She has subsequently recovered without incident. Diagnosis and accurate classification of megaduodenum requires surgical exploration with a full-thickness biopsy and subsequent histopathologic analysis to rule out obstructive or functional disorders of the duodenum. Treatment of megaduodenum depends on the underlying cause and degree of duodenal distention. It is crucial that clinicians are knowledgeable of the various surgical options, their indications, and the potential postoperative complications that may arise.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Idiopathic Megaduodenum in a Teenager: A Case Report

Eze,

Chime

et al. 2024

Cureus

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“…Complications of surgery are also a possible cause. The main causes of mechanical megaduodenum in adulthood are annular pancreas, adhesions, tumors, inflammatory lesions, aneurysms, and superior mesenteric artery syndrome [2], [6], [7], [8], [9], [10], [11]. Some other less common causes of mechanical megaduodenum are foreign bodies, parasites, and webs.…”

Section: Discussionmentioning

confidence: 99%

“…Table 1 summarizes the main cases of megaduodenum described in the literature [1], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25]. Patients with megaduodenum often have abdominal distention, nausea, vomiting diarrhea, and malnutrition, especially in chronic cases and late presentation.…”

Section: Discussionmentioning

confidence: 99%

A rare case of idiopathic congenital megaduodenum in adult misinterpreted during childhood: case report and literature review

Horvat

Brentano

Abe

et al. 2019

Radiology Case Reports

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Intestinal malformations are common disorders in newborn and favorable outcomes have been reported for such conditions. Although, if the patient is treated in a not experienced center, misinterpretation of the clinical and radiological findings may lead to errors in treatment and possible complications in adulthood. We report a case of a congenital megaduodenum which was misinterpreted as an intestinal malrotation resulting in late complications. The patient underwent a successful surgical resection of the duodenum with improvement of his clinical symptoms and nutritional status. This case report emphasizes the importance of considering megaduodenum in the differential diagnosis of patients with feeding impairment, even during adulthood. Early diagnosis and treatment may improve patients’ outcome and reduce morbidity.

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“…Massive overwhelming strongyloidiasis may cause intestinal obstruction, ileus, GI bleeding, and megaduodenum. Adult worms can invade the intestinal mucosa and produce an inflammatory response, involving mono -nuclear cells and eosinophils (9,10).…”

Section: Discussionmentioning

confidence: 99%

An Unusual Presentation of Duodenal Strongyloides stercoralis Enteritis Ulcerative Colitis Patient: A Case Report

Hamidian¹,

Seyfi²

2016

Arch Crit Care Med

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Introduction: Strongyloidiasis is a parasitic disease, which is more prevalent in tropical regions of the world. It is usually found in a chronic and limited disease form yet in some immunocompromised patients, it may become a life -threatening disease. Case Presentation: A 55 -year -old female, who was a known case for ulcerative colitis, referred to the hospital with nausea and vomiting. The patient was diagnosed with Strongyloidiasis due to Strongyloides stercoralis larvae, detected in the stool examination test and the biopsy specimens taken from the duodenum. The patient received subcutaneous ivermectin and reached a complete recovery. Conclusions: Strongyloides stercoralis often causes chronic and clinically asymptomatic infection; parasite number can increase substantially in the immunocompromised host, leading to hyperinfection, dissemination, and death if unrecognized. It is noteworthy to mention that screening for Strongyloides infection before the initiation of immunosuppressive therapy should be considered, particularly in endemic areas.

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Megaduodenum associated with gastric strongyloidiasis

Cited by 5 publications

References 9 publications

Idiopathic Megaduodenum in a Teenager: A Case Report

Idiopathic Megaduodenum in a Teenager: A Case Report

A rare case of idiopathic congenital megaduodenum in adult misinterpreted during childhood: case report and literature review

An Unusual Presentation of Duodenal Strongyloides stercoralis Enteritis Ulcerative Colitis Patient: A Case Report

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