Meibomian gland dysfunction and blepharitis: A common and still unsolved ophthalmic problem

Kudasiewicz-Kardaszewska, Agnieszka; Grant-Kels, Jane M.; Grzybowski, Andrzej

doi:10.1016/j.clindermatol.2023.08.005

Cited by 2 publications

(1 citation statement)

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“…Consequently, these factors causing the reduction of tear secretion lead to dry eye symptoms. In addition, meibomian gland dysfunction and chronic blepharitis often occurring among SSc patients could increase symptoms of DED [13] (see Figure 4). Depending on the study the prevalence of systemic sclerosis patients with DED varies from 37% to 79% [7,12].…”

Section: Dry Eye Diseasementioning

confidence: 99%

Ocular Manifestation in Systemic Sclerosis—A Literature Review

Paczwa,

Rerych,

Romanowska-Próchnicka

et al. 2024

Life

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Systemic sclerosis (SSc) is a chronic autoimmune connective tissue disease that affects more than 2 million people worldwide. It manifests through vasculopathy, an abnormal immunological response, and fibrosis leading to dysfunction of the multiple organs. The disease is categorized into two subtypes: limited cutaneous SSc and diffuse cutaneous SSc. Scleroderma can affect vital organs with respiratory, cardiac, renal, ocular, and dermatological complications. The ocular manifestations of the disease can occur in the anterior and posterior segments of the eye. Changes in the anterior segment related to the disease include eyelid skin remodeling, dry eye syndrome, and conjunctival abnormalities. The disease’s impact on the posterior segment of the eye mostly causes pathologies in the retinal microcirculatory system and abnormalities in the optic nerve. This review provides detailed insights into ocular complications associated with scleroderma.

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Section: Dry Eye Diseasementioning

confidence: 99%