Melanocytic Naevi

Kinsler, Veronica A.

doi:10.1002/9781119142812.ch105

Cited by 1 publication

(2 citation statements)

References 167 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 The superimposed lesions may appear in wide ranges of sizes ranging from a 1 to 100 mm. [3][4][5] Both NS and SLN are commonly asymptomatic. Epidemiologically, PPK is more commonly present in males with a ratio of 12:5.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Noninvasive imaging exploration of phacomatosis pigmentokeratotica using high‐frequency ultrasound and optical coherence tomography: Can biopsy of PPK patients be avoided?

Lee

Benavides

Manwar

et al. 2023

Skin Research and Technology

View full text Add to dashboard Cite

Background Phacomatosis pigmentokeratotica (PPK) is a distinct and rare type of epidermal nevus syndrome characterized by coexisting nonepidermolytic organoid sebaceous nevus (SN) with one or more speckled lentiginous nevi (SLN). Atypical nevi including compound Spitz and compound dysplastic may manifest within regions of SLN. Patients with PPK, or similar atypical nevus syndromes, may be subject to a significant lifetime number of biopsies, leading to pain, scarring, anxiety, financial burden, and decreased quality of life. The current literature includes case reports, genetics, and associated extracutaneous symptoms of PPK, but use of noninvasive imaging techniques have not been explored. We aim to investigate the value of high‐frequency ultrasound (HFUS) and optical coherence tomography (OCT) in discriminating morphological features of pigmented lesions and nevus sebaceous within one patient with PPK. Materials and methods Two modalities, (1) HFUS imaging, based on acoustic properties and (2) OCT imaging, based on optical properties, were used to image a patient with PPK. Benign pigmented lesions, which may raise clinical suspicion for significant atypia, and nevus sebaceous, were selected on different areas of the body to be studied. Results Five pigmented lesions and one area of nevus sebaceous were imaged and analyzed for noninvasive features. Distinct patterns of hypoechoic features were seen on HFUS and OCT. Conclusion HFUS provides a deep view of the tissue, with ability to differentiate gross structures beneath the skin. OCT provides a smaller penetration depth and a higher resolution. We have described noninvasive features of atypical nevi and nevus sebaceous on HFUS and OCT, which indicate benign etiology.

show abstract

Section: Introductionmentioning

confidence: 99%

“…The coexisting SLN, otherwise known as nevus spilus, is described as larger café‐au‐lait macules with numerous smaller superimposed darker black or brown melanocytic proliferations 3 . The superimposed lesions may appear in wide ranges of sizes ranging from a 1 to 100 mm 3–5 . Both NS and SLN are commonly asymptomatic.…”

Section: Introductionmentioning

confidence: 99%