Melanose da margem palpebral com suspeita de malignidade: relato de caso

Oliveira, Claudia Akemi Shiratori de; Barros, João; Souza, Simone de Biagi; Cvintal, Tadeu; Schellini, Silvana Artioli

doi:10.1590/s0004-27492009000500022

Cited by 2 publications

(1 citation statement)

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“…A case of a patient with an irregular pigmented lesion of the lower eyelid margin simulating malignant tumor, which was treated based on the results of IC and diagnosed with secondary melanosis by histology, was presented in 2009. The importance of IC was emphasized as an effective and safe method circumventing unnecessary and extensive procedures (11) . A few melanocytic lesions, including four nevi and one melanoma, were examined in another study, and for such cases, results of both IC and histopathological features correlated (5) .…”

Section: Application Of Ic In the Evaluation Of Lesions Of Melanocytimentioning

confidence: 99%

Impression cytology in the evaluation of ocular surface tumors: review article

Barros¹,

Almeida²,

Lowen³

et al. 2015

Arquivos Brasileiros De Oftalmologia

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Impression cytology (IC) has been widely used as a method for evaluating the ocular surface and superficial cells layers in the diagnosis and follow-up after treatment of several ocular surface tumors of both epithelial and melanocytic origin. Information regarding this can be found in the English-language literature since 1992. Using either cellulose acetate or Biopore membranes for specimen collection, a high correlation has been found between IC and tissue histology. Compared with exfoliative cytology with spatula, IC is less traumatic to the patient's eye, provides a precise location of the area being studied, and allows accurate observation of the cells the way they exist in vivo. The additional advantage of IC is the preservation of limbal stem cells responsible for continuous corneal epithelium renewal; these can be affected after incisional or excisional biopsy at the corneoscleral limbus, which is the most frequent site of appearance of tumors in the stratified epithelium. Treatment for ocular surface squamous neoplasia has historically included surgery, but nonsurgical interventions have also been adopted. Hence, in certain cases, ophthalmologists may prefer interventions less invasive than surgical biopsy such as of impression cytology for both initial diagnosis and therapeutic monitoring of treatment for ocular surface lesions. Nevertheless, it should be considered that IC may be less helpful if the results conflict with the clinical picture or if the clinical diagnosis is uncertain and results are negative. In such cases, surgical biopsy is required for accurate diagnosis. The purpose of this review is to examine the published literature on the utilization of IC for the diagnosis and management of ocular surface tumors and to discuss the requirement for further investigation on the subject.

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Section: Application Of Ic In the Evaluation Of Lesions Of Melanocytimentioning

confidence: 99%