Melatonin increases superoxide dismutase 2 (SOD2) levels and improves rat ovarian graft function after transplantation
Karla Krislane Alves Costa Monteiro,
Luciana Lamarão Damous,
Marcos Eiji Shiroma
et al.
Abstract:Background
Ovarian cryopreservation is a promising technique despite being hindered by damage from freezing and thawing. Melatonin can mitigate this outcome.
Objective
This study aimed to evaluate the effect of melatonin on the follicular dynamics of ovarian tissue in a cryopreserved cell culture.
Methods
Three-month-old adult female Wistar rats (
n
= 24) weighing approximately 250 g were oophorectomized and divided… Show more
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