Melena as Initial Presentation of Adenocarcinoma in Pancreatic Tail

Abstract

Melena associated with gastric varices, in the setting of possible obstructing pancreatic adenocarcinoma, has been poorly documented as an initial presenting sign for pancreatic malignancy. Considering the late presentation of patients with pancreatic malignancy, it is important to consider all potential presenting symptoms for the early detection and treatment of pancreatic malignancy. Below, we present a patient with no history of liver pathology, who presents with melena and gastric varices, likely relating to portal hypertension in the setting of an obstructing pancreatic malignancy.

Pancreatic tumor with lung tumor: a case report

“…However, these features are not always strictly present together. 4 There was splenomegaly on physical examination, and the AST/ALT levels were normal, but we were unable to do an endoscopy operation since the patient refused. Due to history of melena and hematemesis, we believe she had esophageal varices.…”

Pancreatic head cancer with gastrointestinal bleeding as the initial manifestation: a case report and literature review

“…We found a total of 21 case reports of pancreatic cancer presenting as GIB in the past 20 years (Table 1). [1,[4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] By summarizing the literature, we think pancreatic cancer presenting as GIB has several mechanisms: 1. The tumor directly Higashiyama et al [17] 69/- invades gastrointestinal tract, such as the stomach, duodenum, and colon; 2.…”