Membranous Nephropathy Associated with the Relatively Selective Cyclooxygenase-2 Inhibitor, Etodolac, in a Patient with Early Rheumatoid Arthritis

Abstract

Abstract

p-Toluenesulfonic acid-promoted organic transformations for the generation of molecular complexity

“…In particular, tetrahydropyrano[3,4- b ]indoles have potent antifungal and antibacterial activities, whereas tetrahydro-β-carbolines are known to have antiviral, antiprotozoal, serotonin receptor (5HT) antagonistic, and anticancer properties. 111 Recently, Ghorai et al 112 presented a method (Scheme 68) for the stereoselective synthesis of different 1,4-disubstituted tetrahydro-β-carbolines and tetrahydropyrano[3,4- b ]indoles with high yield. In this two-step, one-pot three-component process, the aziridines/epoxides ring is first broken by LiClO 4 -catalysed S N 2-type reaction using indoles followed by Pictet–Spengler reaction catalysed by p -toluenesulfonic acid.…”

Glomerulonefritis membranosa asociada al uso de analgésicos antiinflamatorios no esteroideos. Reporte de caso

“…El síndrome nefrótico por el uso de AINE debido a nefropatía membranosa, es poco frecuente y debe ser reconocido como una reacción medicamentosa idiosincrática para muchos AINE (30,31). Otras revisiones consideran un proceso de hipersensibilidad (31).…”

Drug-induced Kidney Disease – Pathology and Current Concepts

“…There are numerous drugs and chemicals associated with MGN, best known among them being gold and penicillamine. Others include NSAIDS, 44 certain COX-2 inhibitors, 45 mercury, [46][47][48] captopril, 49,50 lithium 51 (also implicated in MCD 52 ), formaldehyde, 53 trimethadione 54 (anti-convulsant), probenecid 55 and 2-Mercaptopropionyl glycine 56 (synthetic antioxidant used in the treatment of cystinuria, and rheumatic, skin and liver disorders). Druginduced and idiopathic MGN have remarkably similar morphologic features.…”